Amines REACH

p-toluidine

CAS Number
106-49-0
EC Number
203-403-1

What is p-toluidine?

p-Toluidine (CAS 106-49-0), also known as p-tolylamine and 4-toluidine, is an aromatic amine used as a chemical intermediate in the synthesis of dyes, pigments, and specialty compounds.

Where is p-toluidine used?

  • Dye and pigment manufacturing: key intermediate for azo dyes in textile dyeing and leather finishing
  • Rubber and elastomer production: curing and cross-linking agent controlling vulcanization characteristics
  • Printing inks and packaging coatings: synthesis of colorants
  • Personal care and cosmetics: precursor in hair dye intermediates
  • It also serves in oxidative colorant systems for professional salon products.

Commercial specifications

  • Technical grade, purity typically 99% and above
  • Packaging in drums and bulk quantities for industrial-scale procurement

Other Names (Synonyms)

p-tolylamine|p-Methylbenzenamine|4-toluidine|4-methylaniline|4-aminotoluene|4-Methylbenzenamine|p-Methylaniline|Benzenamine, 4-methyl-

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What are the physical properties of p-toluidine?

Melting Point 44-45 °C
Boiling Point 200.4 °C
Density 1.046 g/cm³ @ Temp: 20 °C
Flash Point 192 °F
Appearance White lustrous plates or leaflets. Soluble in alcohol and ether; very slightly soluble in water. Combustible.
Color tan to brown
Form powder
Water Solubility 1.1 g/100 mL
Vapor Pressure 0.26 mm Hg ( 25 °C)
Refractive Index 1.5636
pH 7.8 (7g/L)
Log P 1.39-1.44 at pH7.4-7.5

How is p-toluidine classified and handled safely? Learn More

Danger
GHS06· Toxic GHS08· Health Hazard GHS09· Environmental Hazard GHS07· Irritant

Hazard Statements

H301 Toxic if swallowed
H302 Harmful if swallowed
H311 Toxic in contact with skin
H315 Causes skin irritation

Precautionary Statements

P203 Obtain, consult and follow expert instructions for use.
P260 Do not breathe dust/fume/gas/mist/vapours/spray.
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P262 Do not get in eyes, on skin, or on clothing.

Which trade and regulatory codes apply to p-toluidine?

HS Code 38220000
UN Number 3451
ADR Class 6.1
Packing Group II
Storage Class 6.1A - Combustible acute toxic Cat. 1 and 2 very toxic hazardous materials
WGK (Germany) 2
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