Amines REACH

o-toluidine

CAS Number
95-53-4
EC Number
202-429-0

What is o-toluidine?

o-Toluidine (CAS 95-53-4), also known as o-tolylamine, is an aromatic amine used as a chemical intermediate in the synthesis of dyes, pigments, and curing agents.

Where is o-toluidine used?

  • Dyes and pigments: key precursor in the production of azo dyes used to color textiles, leather, and paper substrates
  • Printing inks: pigments derived from these intermediates achieve specific hue ranges in packaging and commercial printing
  • Resin systems: curing agent component and cross-linker that hardens coatings and high-performance adhesives
  • Personal care: derived colorants in formulations requiring specific synthetic dye chemistry
  • It serves as a building block where a reactive amine group is required to produce more complex organic compounds.

Commercial specifications

  • Purity specifications commonly 99% and above
  • Drum and IBC quantities

Other Names (Synonyms)

ortho-toluidine|o-tolylamine|o-Methylbenzenamine|o-methylaniline|o-aminotoluene|2-Toluidine|2-Methylbenzenamine|2-Methylbenzamine

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What are the physical properties of o-toluidine?

Melting Point -16.3 °C
Boiling Point 200.3 °C
Density 1.008 g/cm³ @ Temp: 20 °C
Flash Point 185 °F
Appearance Light-yellow liquid, becomes reddishbrown on exposure to air and light. Soluble in alcohol and ether; very slightly soluble in water. Combustible.
Color light yellow to light amber
Odor Aromatic, aniline-like.
Form liquid
Water Solubility 1.5 g/100 mL (25 ºC)
Vapor Pressure 0.26 mm Hg ( 25 °C)
Refractive Index n 20/D 1.572(lit.)
pH 7.4 (H2O, 20℃)Aqueous solution
Log P 1.4 at 24.5℃

How is o-toluidine classified and handled safely? Learn More

Danger
GHS06· Toxic GHS08· Health Hazard GHS09· Environmental Hazard GHS07· Irritant

Hazard Statements

H227 Combustible liquid
H301 Toxic if swallowed
H302 Harmful if swallowed
H312 Harmful in contact with skin

Precautionary Statements

P203 Obtain, consult and follow expert instructions for use.
P210 Keep away from heat, hot surfaces, sparks, open flames and other ignition sources. No smoking.
P260 Do not breathe dust/fume/gas/mist/vapours/spray.
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.

Which trade and regulatory codes apply to o-toluidine?

HS Code 29214300
UN Number 2920
ADR Class 8
Packing Group I
Storage Class 6.1A - Combustible acute toxic Cat. 1 and 2 very toxic hazardous materials
WGK (Germany) 3
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