SoleChem

4-cyanopyridine

CAS
100-48-1
EC
202-856-7
Mol. Weight
104.11 g/mol

Description

4-Cyanopyridine (CAS 100-48-1), also known as isonicotinic acid nitrile and abbreviated as 4-CP, is a pyridine-based nitrile building block used across pharmaceutical synthesis and specialty chemical manufacturing.

It functions primarily as a reactive intermediate, enabling the construction of more complex heterocyclic structures through its dual nitrile and pyridine functionalities in various chemical processes.

In pharmaceutical manufacturing, 4-CP is a key precursor in the synthesis of antifungal agents, antivirals, and other nitrogen-containing active pharmaceutical ingredients for the global market.

It is used in the production of ligands and coordination complexes that serve as catalysts or catalyst precursors in organometallic chemistry and advanced material science applications.

Agrochemical formulators use it as a building block for pyridine-derived herbicides and fungicides. In flavor chemistry, isonicotinic acid nitrile contributes to select fragrance and flavor compound synthesis.

This is particularly useful where pyridine-ring structures are required. 4-Cyanopyridine is supplied as a white to off-white crystalline solid for industrial and laboratory use.

Standard commercial grades include technical and high-purity specifications suitable for pharmaceutical intermediate and research applications. Packaging typically ranges from kilogram-scale to bulk orders.

Our supply chain ensures consistent quality for multi-hundred kilogram bulk orders for industrial synthesis. We maintain strict adherence to safety and handling protocols for all chemical shipments.

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Physical Properties

Melting Point 79 °C
Boiling Point 78 °C @ Press: 6 Torr
Density 1.1145 (rough estimate)
Flash Point 88 °C
Appearance The cyanopyridines are as follows: 2-cyano-: A white to tan liquid or solid. Almond odor. Boiling point=2213℃ ; freezing/melting point=27℃ ; flash point=89℃ . 3-cyano-: a colorless liquid or gray crystal- line solid.
Color White to off-white
Form Crystals or Powder
Water Solubility 3.2 g/100ml (16.4 ºC)
Vapor Pressure 41.9Pa at 25℃
Refractive Index 1.5242 (estimate)
Log P 0.46 at 25℃

Safety & Handling (Learn More)

Warning GHS07
Hazard Statements
H302 H302
H312 H312
H319 H319
H332 H332
Precautionary Statements
P261 P261
P264 P264
P270 P270
P271 P271
P280 P280
P317 P317
P321 P321
P330 P330
P501 P501
P264+P265 P264+P265
P301+P317 P301+P317
P302+P352 P302+P352
P304+P340 P304+P340
P337+P317 P337+P317
P362+P364 P362+P364
P305+P351+P338 P305+P351+P338

Trade & Regulatory

HS Code 29333999
Storage Class 11 - Combustible Solids
WGK (Germany) 3

Documentation

Other Names

4-Pyridinecarbonitrile|pyridine-4-carbonitrile|Isonicotinic acid nitrile|BY3226D010|γ-Cyanopyridine|p-Cyanopyridine|4-CP

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