4-cyanopyridine
Description
4-Cyanopyridine (CAS 100-48-1), also known as isonicotinic acid nitrile and abbreviated as 4-CP, is a pyridine-based nitrile building block used across pharmaceutical synthesis and specialty chemical manufacturing.
It functions primarily as a reactive intermediate, enabling the construction of more complex heterocyclic structures through its dual nitrile and pyridine functionalities in various chemical processes.
In pharmaceutical manufacturing, 4-CP is a key precursor in the synthesis of antifungal agents, antivirals, and other nitrogen-containing active pharmaceutical ingredients for the global market.
It is used in the production of ligands and coordination complexes that serve as catalysts or catalyst precursors in organometallic chemistry and advanced material science applications.
Agrochemical formulators use it as a building block for pyridine-derived herbicides and fungicides. In flavor chemistry, isonicotinic acid nitrile contributes to select fragrance and flavor compound synthesis.
This is particularly useful where pyridine-ring structures are required. 4-Cyanopyridine is supplied as a white to off-white crystalline solid for industrial and laboratory use.
Standard commercial grades include technical and high-purity specifications suitable for pharmaceutical intermediate and research applications. Packaging typically ranges from kilogram-scale to bulk orders.
Our supply chain ensures consistent quality for multi-hundred kilogram bulk orders for industrial synthesis. We maintain strict adherence to safety and handling protocols for all chemical shipments.
Physical Properties
| Melting Point | 79 °C |
| Boiling Point | 78 °C @ Press: 6 Torr |
| Density | 1.1145 (rough estimate) |
| Flash Point | 88 °C |
| Appearance | The cyanopyridines are as follows: 2-cyano-: A white to tan liquid or solid. Almond odor. Boiling point=2213℃ ; freezing/melting point=27℃ ; flash point=89℃ . 3-cyano-: a colorless liquid or gray crystal- line solid. |
| Color | White to off-white |
| Form | Crystals or Powder |
| Water Solubility | 3.2 g/100ml (16.4 ºC) |
| Vapor Pressure | 41.9Pa at 25℃ |
| Refractive Index | 1.5242 (estimate) |
| Log P | 0.46 at 25℃ |
Safety & Handling (Learn More)
Trade & Regulatory
| HS Code | 29333999 |
| Storage Class | 11 - Combustible Solids |
| WGK (Germany) | 3 |
Documentation
Other Names
4-Pyridinecarbonitrile|pyridine-4-carbonitrile|Isonicotinic acid nitrile|BY3226D010|γ-Cyanopyridine|p-Cyanopyridine|4-CP
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