Pyrrole

CAS Number
109-97-7
EC Number
203-724-7
Chemical Formula
C4H5N
Molecular Weight
67.09 g/mol
FEMA Number
FEMA 3386

Description

Pyrrole (CAS 109-97-7), also known by its older designations pyrrhol and imidole, is a five-membered nitrogen-containing heterocycle used as a key synthetic building block across pharmaceutical and agrochemical manufacturing. Its reactivity at multiple ring positions makes it a high-demand intermediate for constructing complex molecular architectures in commercial synthesis workflows and advanced materials production for global industrial sectors.

In pharmaceutical manufacturing, this compound serves as a precursor to a broad range of active ingredients, including antifungal agents and kinase inhibitors, where the intact ring is incorporated into the final drug structure. Agrochemical producers use it to synthesize pyrrole-based insecticides and fungicides, with chlorfenapyr being one of the most commercially significant derivatives currently utilized in the global agricultural market.

In polymer and materials science, it undergoes oxidative polymerization to produce polypyrrole, a conductive polymer used in antistatic coatings, biosensors, and various energy storage applications for modern electronics. It also carries FEMA 3386 status, supporting its use as a flavor ingredient in food and beverage formulations at trace concentrations, adhering to strict safety guidelines for food-grade chemical additives.

The product is supplied as a liquid in standard commercial and high-purity grades. Technical grade material is available for polymer synthesis, while reagent grades serve pharmaceutical and biotechnology applications. Packaging typically ranges from small containers for laboratory procurement to bulk quantities for industrial-scale users, ensuring flexible supply chain solutions for diverse manufacturing requirements and research needs.

Other Names (Synonyms)

pyrrhol|azole|imidole|1-aza-2,4-cyclopentadiene|1H-pyrrole|Pyrrol

Key Technical Features

  • High Purity Grade standard
  • Consistent Batch Quality
  • Full Regulatory & REACH Support
  • Global Logistics Network enabled

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Physical Properties

Melting Point -23.4 °C
Boiling Point 129.7 °C
Density 0.9698 g/cm³ @ Temp: 20 °C
Flash Point 92 °F
Appearance colourless to brown liquid with chloroform odour
Color Clear almost colorless to brownish
Odor at 0.10 % in propylene glycol. sweet warm nutty ethereal
Form Liquid
Water Solubility 60 g/L (20 ºC)
Vapor Pressure 8.7 hPa (20 °C)
Refractive Index n 20/D 1.508(lit.)
pH >6 (10g/l, H2O, 20℃)
Log P 0.85

Documentation

Safety & Handling Learn More

Warning
GHS02· Flammable GHS07· Irritant

Hazard Statements

H226 Flammable liquid and vapor
H302 Harmful if swallowed

Precautionary Statements

P210 Keep away from heat, hot surfaces, sparks, open flames and other ignition sources. No smoking.
P233 Keep container tightly closed.
P240 Ground and bond container and receiving equipment.
P241 Use explosion-proof [electrical/ventilating/lighting/…] equipment.

Trade & Regulatory

HS Code 29339900
UN Number 1992
ADR Class 3
Packing Group III
Storage Class 3 - Flammable liquids
WGK (Germany) 2
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