3-methyl-5-pyrazolone

CAS Number
108-26-9
EC Number
203-565-3

What is 3-methyl-5-pyrazolone?

3-Methyl-5-pyrazolone (CAS 108-26-9) is a pyrazolone building block used primarily as a chemical intermediate in the synthesis of azo dyes, pigments, and pharmaceutical compounds.

Where is 3-methyl-5-pyrazolone used?

  • Colorants: key coupling component via its reactive methylene group; starting material for API synthesis
  • Dye and pigment production: couples with diazonium salts to give yellow and orange azo colorants for textile, leather, and paper dyeing
  • Printing inks: derived pigments for packaging inks needing color fastness and substrate adhesion
  • Pharmaceutical synthesis: precursor to pyrazolone-based APIs and intermediates, including analgesic and anti-inflammatory classes
  • Specialty chemicals: heterocyclic compounds for agrochemical and research applications

Commercial specifications

  • Bulk quantities in multi-kilogram and metric ton packaging

Other Names (Synonyms)

3-methyl-1,4-dihydropyrazol-5-one|3-methyl-2-pyrazolin-5-one

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What are the physical properties of 3-methyl-5-pyrazolone?

Melting Point 217-219 °C
Boiling Point 183.6°C (rough estimate)
Density 1.1890 (rough estimate)
Appearance Yellowish powder
Color White to Light yellow
Form powder to crystal
Refractive Index 1.4327 (estimate)

How is 3-methyl-5-pyrazolone classified and handled safely? Learn More

Warning
GHS09· Environmental Hazard

Hazard Statements

H400 Very toxic to aquatic life
H410 Very toxic to aquatic life with long lasting effects

Precautionary Statements

P273 Avoid release to the environment.
P391 Collect spillage.
P501 Dispose of contents/container in accordance with local regulations.

Which trade and regulatory codes apply to 3-methyl-5-pyrazolone?

HS Code 29331990
WGK (Germany) 3
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