3-methyl-5-pyrazolone

CAS Number
108-26-9
EC Number
203-565-3
Chemical Formula
C4H6N2O
Molecular Weight
98.10 g/mol

Description

3-Methyl-5-pyrazolone (CAS 108-26-9) is a pyrazolone building block used primarily as a chemical intermediate in the synthesis of azo dyes, pigments, and pharmaceutical compounds. Its reactive methylene group makes it a key coupling component in colorant manufacturing and a starting material for active pharmaceutical ingredient (API) synthesis.

In dye and pigment production, it couples with diazonium salts to produce yellow and orange azo colorants used across textile, leather, and paper dyeing processes. Printing ink formulators rely on these derived pigments for packaging inks where color fastness and substrate adhesion are critical performance requirements.

In pharmaceutical synthesis, it serves as a precursor to pyrazolone-based APIs and intermediates, including analgesic and anti-inflammatory compound classes. Specialty chemical manufacturers also use it in the production of heterocyclic compounds for agrochemical and research applications.

3-Methyl-5-pyrazolone is supplied as an off-white to pale yellow crystalline powder. Technical grade is the standard commercial offering for industrial use. Pharmaceutical-grade material is available to meet API intermediate specifications. Bulk quantities are typically offered in multi-kilogram and metric ton packaging.

Other Names (Synonyms)

3-methyl-1,4-dihydropyrazol-5-one|3-methyl-2-pyrazolin-5-one

Key Technical Features

  • High Purity Grade standard
  • Consistent Batch Quality
  • Full Regulatory & REACH Support
  • Global Logistics Network enabled

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Physical Properties

Melting Point 217-219 °C
Boiling Point 183.6°C (rough estimate)
Density 1.1890 (rough estimate)
Appearance Yellowish powder
Color White to Light yellow
Form powder to crystal
Refractive Index 1.4327 (estimate)

Safety & Handling (Learn More)

Warning
GHS09· Environmental Hazard

Hazard Statements

H400 Very toxic to aquatic life
H410 Very toxic to aquatic life with long lasting effects

Precautionary Statements

P273 Avoid release to the environment.
P391 Collect spillage.
P501 Dispose of contents/container in accordance with local regulations.

Trade & Regulatory

HS Code 29331990
WGK (Germany) 3

Documentation

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