SoleChem

4-methylpyridine

CAS
108-89-4
EC
203-626-4
Mol. Weight
93.13 g/mol

Description

4-Methylpyridine (CAS 108-89-4) is a pyridine-based heterocyclic building block used across pharmaceutical synthesis, agrochemical manufacturing, and specialty chemical production. It functions primarily as a reactive intermediate and catalyst.

In pharmaceuticals, it serves as a key precursor in the synthesis of isonicotinic acid derivatives and active pharmaceutical ingredients targeting cardiovascular and neurological conditions. Agrochemical producers use it to manufacture herbicides.

In coatings and adhesive formulations, it acts as a curing catalyst and crosslinking accelerator for epoxy systems, influencing cure rate and final film performance. It is also known as p-picoline or gamma-picoline.

At trace concentrations, it contributes roasted and nutty flavor notes in food applications, with usage governed by FEMA-recognized flavor standards. This versatility makes it essential for various industrial sectors.

The compound is supplied as a liquid at standard commercial purities, typically 98% and 99%+ grades for pharmaceutical and synthesis applications. Technical-grade material is available for industrial catalyst use.

Packaging ranges from drums to ISO tank quantities depending on volume requirements. Our supply chain ensures consistent quality meeting USP and FCC standards where applicable for specific high-purity industrial needs.

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Physical Properties

Melting Point 3.66 °C
Boiling Point 145 °C @ Press: 760 Torr
Density 0.9548 g/cm³ @ Temp: 20 °C
Flash Point 134 °F
Appearance Picolines are colorless liquids. Strong, unpleasant, pyridine-like odor.“Picoline” is often used as mixed isomers.
Color Clear light yellow
Odor Obnoxious, Sweetish
Form Liquid
Water Solubility soluble
Vapor Pressure 4 mm Hg ( 20 °C)
Refractive Index n 20/D 1.504(lit.)
Log P 1.22 at 25℃

Safety & Handling (Learn More)

Danger GHS02 GHS06 GHS07 GHS08
Hazard Statements
H226 H226
H302 H302
H311 H311
H315 H315
H319 H319
H332 H332
H335 H335
H336 H336
H372 H372
Precautionary Statements
P210 P210
P233 P233
P240 P240
P241 P241
P242 P242
P243 P243
P260 P260
P261 P261
P262 P262
P264 P264
P270 P270
P271 P271
P280 P280
P316 P316
P317 P317
P319 P319
P321 P321
P330 P330
P405 P405
P501 P501
P264+P265 P264+P265
P301+P317 P301+P317
P302+P352 P302+P352
P304+P340 P304+P340
P332+P317 P332+P317
P337+P317 P337+P317
P361+P364 P361+P364
P362+P364 P362+P364
P370+P378 P370+P378
P403+P233 P403+P233
P403+P235 P403+P235
P303+P361+P353 P303+P361+P353
P305+P351+P338 P305+P351+P338

Trade & Regulatory

HS Code 29333955
UN Number 1992
ADR Class 3
Packing Group III
Storage Class 3 - Flammable liquids
WGK (Germany) 1

Documentation

Other Names

p-picoline|p-methylpyridine|gamma-picoline|4-picoline|4-Mepy|Pyridine, 4-methyl-|gamma-Methylpyridine|Ba 35846|4-MP

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