Pyrrolidine
Description
Pyrrolidine (CAS 123-75-1), also known as Azolidine, is a saturated five-membered nitrogen heterocycle used as a flavoring agent and chemical intermediate across food, pharmaceutical, and personal care industries.
Assigned FEMA 3523, it functions as a building block for synthesizing active ingredients and flavor compounds rather than as a finished additive in its own right for most industrial applications.
In food and flavor manufacturing, it is used to produce thermally derived flavor compounds that contribute roasted, grain, and savory notes to processed foods and beverages during the production cycle.
Pharmaceutical formulators rely on it as a key synthetic intermediate for APIs, where the pyrrolidine ring is incorporated into drug candidates targeting a range of therapeutic categories and medical needs.
In personal care, it supports the synthesis of conditioning agents and specialty amines used in hair and skin formulations. Agrochemical producers also use it as an intermediate in fungicide and pesticide synthesis.
Pyrrolidine is supplied as a colorless to pale yellow liquid in standard drum and IBC packaging. Technical and reagent grades are the most commonly available for industrial and laboratory procurement needs.
High-purity pharmaceutical-grade material is offered for API synthesis applications. Buyers should confirm purity specifications and moisture content with suppliers, as grade requirements vary significantly by end use.
Material quality is often verified against internal manufacturer specifications or recognized standards such as USP, Ph.Eur., BP, EP, FCC, or ACS depending on the specific grade and application.
Physical Properties
| Melting Point | -63 °C |
| Boiling Point | 86.71 °C |
| Density | 0.8520 g/cm³ @ Temp: 22.5 °C |
| Flash Point | 37 °F |
| Appearance | colourless to pale yellow liquid with a penetrating |
| Color | Colorless to Almost colorless |
| Odor | at 0.10 % in propylene glycol. ammoniacal animal egg amine |
| Form | Liquid |
| Water Solubility | Miscible with alcohol, ether, chloroform and water. |
| Vapor Pressure | 128 mm Hg ( 39 °C) |
| Refractive Index | n 20/D 1.443(lit.) |
| pH | 12.9 (100g/l, H2O, 20℃) |
| Log P | 0.22 at 25℃ |
Safety & Handling (Learn More)
Trade & Regulatory
| HS Code | 29339900 |
| UN Number | 1922 |
| ADR Class | 3 |
| Packing Group | II |
| Storage Class | 3 - Flammable liquids |
| WGK (Germany) | 2 |
Documentation
Other Names
Azolidine|Prolamine|1-Azacyclopentane|Pyrrole, tetrahydro-|2-Imidazolidone
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