3-Pyridinemethanol
Description
3-Pyridinemethanol (CAS 100-55-0), also known as nicotinyl alcohol, is a pyridine-based primary alcohol used across pharmaceutical synthesis, flavoring, and specialty chemical manufacturing.
It functions primarily as a reactive intermediate and surface-active agent, enabling downstream production of more complex molecules and formulations in various industrial sectors.
In pharmaceutical manufacturing, it serves as a key building block for synthesizing active ingredients and drug candidates, particularly where a pyridine-containing alcohol moiety is required.
Food and flavor formulators incorporate it as a flavoring agent, where its characteristic profile contributes to specific taste compositions in approved applications for the food industry.
In polymer and resin systems, it acts as a surface modifier and wetting agent, improving adhesion and substrate compatibility in coatings and plastic formulations for industrial use.
Personal care chemists also evaluate it as a stabilizing component in preservation systems where biocidal or antioxidant activity is needed alongside formulation compatibility and stability.
The material is supplied as a liquid at standard commercial purities, typically ranging from 98% to 99%+ for synthesis-grade material to ensure high performance in chemical reactions.
Pharmaceutical-grade material is available to meet the purity and quality documentation requirements of API and intermediate manufacturing for global regulatory compliance.
Physical Properties
| Melting Point | -6.5 °C |
| Boiling Point | 114 °C @ Press: 12 Torr |
| Density | 1.124 g/mL at 25 °C(lit.) |
| Flash Point | >230 °F |
| Appearance | CLEAR LIGHT YELLOW TO YELLOW LIQUID |
| Color | clear light yellow |
| Form | liquid (clear) |
| Water Solubility | soluble |
| Vapor Pressure | 0.342Pa at 20℃ |
| Refractive Index | n 20/D 1.545(lit.) |
| pH | 7-8 (100g/l, H2O, 20℃) |
| Log P | -0.11 at 25℃ |
Safety & Handling (Learn More)
Trade & Regulatory
| HS Code | 29333999 |
| Storage Class | 10 - Combustible liquids |
| WGK (Germany) | 3 |
Documentation
Other Names
Pyridin-3-ylmethanol|Nicotinyl alcohol
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