Ethyl nicotinate
Description
Ethyl nicotinate (CAS 614-18-6), also known commercially as Ignicut, is the ethyl ester of nicotinic acid used as a pharmaceutical intermediate, flavoring agent, and functional ingredient across multiple industries.
It serves as a building block in the synthesis of active pharmaceutical ingredients and as a precursor in catalyst systems. In pharmaceutical manufacturing, it functions as a key intermediate in the synthesis of niacin derivatives.
Other nicotinic acid-based APIs utilize this compound where ester reactivity drives efficient conversion pathways. Cosmetic formulators incorporate it into topical products targeting skin circulation effects, particularly in warming formulations.
As a flavoring agent, it contributes to tobacco and food flavor profiles where pyridine-type notes are required. It carries a recognized FEMA status supporting its use in regulated flavor applications worldwide.
In catalyst development, it acts as a ligand precursor or coordination compound in heterogeneous and homogeneous catalytic systems. The material is available as a colorless to pale yellow liquid in standard commercial packaging.
It is supplied in pharmaceutical-grade and technical-grade specifications to meet the purity requirements of API synthesis. Certificates of analysis aligned with USP and BP standards are commonly available.
Physical Properties
| Melting Point | 8.5 °C |
| Boiling Point | 121-123 °C @ Press: 0.4 Torr |
| Density | 1.5117 g/cm³ @ Temp: 20 °C |
| Flash Point | 93 °C |
| Appearance | clear colourless to yellow liquid |
| Color | light yellow |
| Form | neat |
| Water Solubility | miscible |
| Vapor Pressure | 4.2-5.5Pa at 20-25℃ |
| Refractive Index | n 20/D 1.504(lit.) |
| Log P | 1.32 |
Safety & Handling (Learn More)
Trade & Regulatory
| HS Code | 29333999 |
| WGK (Germany) | 3 |
Documentation
Other Names
ethyl pyridine-3-carboxylate|3-Pyridinecarboxylic acid, ethyl ester|Ignicut|Nicotinic acid, ethyl ester|Ignocut|Mucotherm|Nicaethan|Nikithan
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