Ethyl nicotinate

CAS Number
614-18-6
EC Number
210-370-7
Chemical Formula
C8H9NO2
Molecular Weight
151.16 g/mol

Description

Ethyl nicotinate (CAS 614-18-6), also known commercially as Ignicut, is the ethyl ester of nicotinic acid used as a pharmaceutical intermediate, flavoring agent, and functional ingredient across multiple industries. It serves as a building block in the synthesis of active pharmaceutical ingredients and as a precursor in catalyst systems. In pharmaceutical manufacturing, it functions as a key intermediate in the synthesis of niacin derivatives.

Other nicotinic acid-based APIs utilize this compound where ester reactivity drives efficient conversion pathways. Cosmetic formulators incorporate it into topical products targeting skin circulation effects, particularly in warming formulations. As a flavoring agent, it contributes to tobacco and food flavor profiles where pyridine-type notes are required. It carries a recognized FEMA status supporting its use in regulated flavor applications worldwide.

In catalyst development, it acts as a ligand precursor or coordination compound in heterogeneous and homogeneous catalytic systems. The material is available as a colorless to pale yellow liquid in standard commercial packaging. It is supplied in pharmaceutical-grade and technical-grade specifications to meet the purity requirements of API synthesis. Certificates of analysis aligned with USP and BP standards are commonly available.

Other Names (Synonyms)

ethyl pyridine-3-carboxylate|3-Pyridinecarboxylic acid, ethyl ester|Ignicut|Nicotinic acid, ethyl ester|Ignocut|Mucotherm|Nicaethan|Nikithan

Key Technical Features

  • High Purity Grade standard
  • Consistent Batch Quality
  • Full Regulatory & REACH Support
  • Global Logistics Network enabled

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Physical Properties

Melting Point 8.5 °C
Boiling Point 121-123 °C @ Press: 0.4 Torr
Density 1.5117 g/cm³ @ Temp: 20 °C
Flash Point 93 °C
Appearance clear colourless to yellow liquid
Color light yellow
Form neat
Water Solubility miscible
Vapor Pressure 4.2-5.5Pa at 20-25℃
Refractive Index n 20/D 1.504(lit.)
Log P 1.32

Safety & Handling (Learn More)

Warning
GHS07· Irritant

Hazard Statements

H319 Causes serious eye irritation

Precautionary Statements

P280 Wear protective gloves/protective clothing/eye protection/face protection.
P264+P265 Wash … thoroughly after handling.
P337+P317 If eye irritation persists: Get medical advice/attention. Get emergency medical help.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.

Trade & Regulatory

HS Code 29333999
WGK (Germany) 3

Documentation

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