Amines REACH

N-Ethylisopropylamine

CAS Number
19961-27-4
EC Number
243-442-1

What is N-Ethylisopropylamine?

N-Ethylisopropylamine (CAS 19961-27-4) is a secondary aliphatic amine used as a reactive intermediate and process chemical in pharmaceutical synthesis, agrochemical manufacturing and polymer chemistry.

Where is N-Ethylisopropylamine used?

  • Pharmaceutical manufacturing: base catalyst in multi-step synthesis routes
  • Agrochemicals: building block in the synthesis of active ingredients
  • Polymer chemistry: polymerization initiation and chain-growth control for specialty resins
  • Formulation development: carrier solvent and pH-adjusting agent
  • It functions as a non-nucleophilic base, pH buffer and initiator where selectivity is critical and competing nucleophilic reactions must be suppressed.

Good to know: Purity tolerance varies significantly between pharmaceutical and industrial applications; buyers should confirm grade suitability against their specific synthesis or formulation requirements before purchase.

Commercial specifications

  • Purity specifications typically range from 97% to 99% or higher depending on the batch
  • Liquid in standard drum and IBC quantities suited to industrial-scale consumption

Other Names (Synonyms)

Isopropylethylamine|n-ethyl-2-propanamine|Etdylisopropylamine|n-ethylpropan-2-amine|Ethylisopropylamine

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What are the physical properties of N-Ethylisopropylamine?

Melting Point -75°C (estimate)
Boiling Point 71.1-71.4 °C
Density 0.71 g/cm³ @ Temp: 20 °C
Flash Point 61 °F
Appearance Colorless to light yellow liqui
Color Colorless to Light yellow
Form clear liquid
Refractive Index n 20/D 1.392(lit.)

How is N-Ethylisopropylamine classified and handled safely? Learn More

Danger
GHS02· Flammable GHS05· Corrosive

Hazard Statements

H225 Highly Flammable liquid and vapor
H314 Causes severe skin burns and eye damage

Precautionary Statements

P210 Keep away from heat, hot surfaces, sparks, open flames and other ignition sources. No smoking.
P233 Keep container tightly closed.
P240 Ground and bond container and receiving equipment.
P241 Use explosion-proof [electrical/ventilating/lighting/…] equipment.

Which trade and regulatory codes apply to N-Ethylisopropylamine?

HS Code 29211990
UN Number 2733
ADR Class 3
Packing Group II
Storage Class 3 - Flammable liquids
WGK (Germany) 3
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