SoleChem

Isobutylamine

Pharmaceutical Intermediates Rubber & Tire
CAS
78-81-9
EC
201-145-4
Mol. Weight
73.14 g/mol

Description

Isobutylamine (CAS 78-81-9), also known by its FEMA 4239 designation, is a primary aliphatic amine used as a reactive building block and process chemical across pharmaceutical synthesis and agrochemical manufacturing.

It functions as an intermediate, pH regulator, and corrosion inhibitor depending on the process context. In agrochemical production, it serves as a key intermediate in synthesizing herbicides and pesticides.

Its reactivity with acid chlorides and isocyanates enables the formation of active ingredient structures. Pharmaceutical manufacturers use it as a synthetic intermediate for drug compounds requiring a branched-chain amine moiety.

In rubber and tire processing, it supports polymerization initiation and acts as an accelerator component in vulcanization systems. Water treatment formulators incorporate it for pH buffering and corrosion inhibition.

These applications are critical in industrial cooling and boiler systems. The product is supplied as a clear, low-viscosity liquid in drum and IBC quantities, with bulk tanker options available for high-volume procurement.

Technical grade is the standard commercial offering, with purity levels typically at 99% or higher. Pharmaceutical-grade material meeting relevant compendial specifications is available from select manufacturers.

This material is suitable for regulated synthesis applications and meets high quality standards. Our logistics network ensures reliable delivery of this essential chemical intermediate to global manufacturing facilities.

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Physical Properties

Melting Point -85 °C
Boiling Point 68-69 °C
Density 0.724 g/cm³ @ Temp: 25 °C
Flash Point 15 °F
Appearance Butyl amines are highly flammable, colorless liquids (n-turns yellow on standing) with ammoniacal or fishlike odors. n-isomer:
Color Clear colorless to slightly yellow
Odor Strong ammoniacal.
Form Liquid
Water Solubility soluble
Vapor Pressure 15.9kPa at 20℃
Refractive Index n 20/D 1.397(lit.)
pH 12.2 (100g/l, H2O, 20℃)
Log P -0.3 at 25℃

Safety & Handling (Learn More)

Danger GHS02 GHS05 GHS06 GHS07
Hazard Statements
H225 Highly Flammable liquid and vapor
H301 Toxic if swallowed
H302 Harmful if swallowed
H311 Toxic in contact with skin
H314 Causes severe skin burns and eye damage
H318 Causes serious eye damage
H331 Toxic if inhaled
H335 May cause respiratory irritation
H301+H311+H331 Toxic if swallowed, in contact with skin or if inhaled
Precautionary Statements
P210 Keep away from heat, hot surfaces, sparks, open flames and other ignition sources. No smoking.
P233 Keep container tightly closed.
P240 Ground and bond container and receiving equipment.
P241 Use explosion-proof [electrical/ventilating/lighting/…] equipment.
P242 Use non-sparking tools.
P243 Take action to prevent static discharges.
P260 Do not breathe dust/fume/gas/mist/vapours/spray.
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P262 Do not get in eyes, on skin, or on clothing.
P264 Wash … thoroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P271 Use only outdoors or in a well-ventilated area.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P316 Get emergency medical help immediately.
P317 Get emergency medical help.
P319 Get medical advice/attention if you feel unwell.
P321 Specific treatment (see … on this label).
P330 Rinse mouth.
P363 Wash contaminated clothing before reuse.
P405 Store locked up.
P501 Dispose of contents/container in accordance with local regulations.
P264+P265 Wash … thoroughly after handling.
P301+P316 Get emergency medical help immediately.
P301+P317 Get emergency medical help.
P302+P352 IF ON SKIN: Wash with plenty of water.
P304+P340 IF INHALED: Remove person to fresh air and keep comfortable for breathing.
P361+P364 Take off immediately all contaminated clothing and wash it before reuse.
P370+P378 Use … for extinction.
P403+P233 Store in a well-ventilated place. Keep container tightly closed.
P403+P235 Store in a well-ventilated place. Keep cool.
P301+P330+P331 Rinse mouth. Do NOT induce vomiting.
P302+P361+P354 IF ON SKIN: Take off immediately all contaminated clothing. Rinse skin with water/shower.
P303+P361+P353 IF ON SKIN (or hair): Take off immediately all contaminated clothing. Rinse skin with water/shower.
P305+P354+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.

Trade & Regulatory

HS Code 29211990
UN Number 1214
ADR Class 3
Packing Group II
Storage Class 3 - Flammable liquids
WGK (Germany) 1

Documentation

Other Names

Valamine|iso-C4H9NH2|I-Butylamine|3-Methyl-2-propylamine|2-Methylpropylamine|2-Methyl-1-Aminopropane|1-Amino-2-methylpropane|IBA

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