Amines REACH

tert-butylamine

CAS Number
75-64-9
EC Number
200-888-1

What is tert-butylamine?

Tert-butylamine (CAS 75-64-9), also known as t-Butylamine or Erbumine, is a primary aliphatic amine used as a chemical building block and pH-regulating agent.

Where is tert-butylamine used?

  • Pharmaceutical manufacturing: forms salt complexes with active ingredients
  • Perindopril erbumine: influences drug stability and bioavailability
  • Agrochemicals: intermediate in herbicides and fungicides, particularly sulfonamide-class compounds
  • Polymer chemistry: polymerization initiator and chain-transfer agent influencing molecular weight distribution in specialty plastics
  • Water treatment: pH buffering in process water systems where controlled alkalinity is required
  • It drives demand from formulators and synthesis chemists sourcing for multi-step production chains.

Good to know: Technical grade is the standard commercial offering; high-purity grades are available for pharmaceutical intermediate applications. Buyers sourcing for regulated end uses typically require documentation supporting GMP-aligned quality standards.

Commercial specifications

  • Liquid in drums, IBCs, and bulk isotanks
  • Low boiling point and specific handling requirements

Other Names (Synonyms)

t-Butylamine|Erbumine|2-Methyl-2-propylamine|2-Methyl-2-propanamine|1,1-Dimethylethylamine|1,1-Dimethylethanamine|2-methylpropan-2-amine|2-Amino-2-methylpropane

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What are the physical properties of tert-butylamine?

Melting Point -66.9 °C
Boiling Point 44 °C
Density 0.6958 g/cm³ @ Temp: 20 °C
Flash Point −36.4 °F
Appearance Butyl amines are highly flammable, colorless liquids (n-turns yellow on standing) with ammoniacal or fishlike odors. n-isomer:
Color Clear
Odor Like ammonia.
Form Liquid
Water Solubility MISCIBLE
Vapor Pressure 5.7 psi ( 20 °C)
Refractive Index n 20/D 1.377(lit.)
pH 12 (100g/l, H2O, 20℃)

How is tert-butylamine classified and handled safely? Learn More

Danger
GHS02· Flammable GHS05· Corrosive GHS06· Toxic GHS07· Irritant

Hazard Statements

H402 Harmful to aquatic life [Hazardous to the aquatic environment, acute hazard]
H412 Harmful to aquatic life with long lasting effects [Hazardous to the aquatic environment, long-term hazard]
H225 Highly Flammable liquid and vapor [Danger Flammable liquids]
H301 Toxic if swallowed [Danger Acute toxicity, oral]
H331 Toxic if inhaled [Danger Acute toxicity, inhalation]

Which trade and regulatory codes apply to tert-butylamine?

HS Code 29211980
UN Number 3286
ADR Class 3
Packing Group II
Storage Class 3 - Flammable liquids
WGK (Germany) 1
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