SoleChem

Isopropanolamine

CAS
78-96-6
EC
201-162-7
Mol. Weight
75.11 g/mol

Description

Isopropanolamine (CAS 78-96-6), also known as MIPA or Threamine, is an amino alcohol used across coatings, personal care, and pharmaceutical manufacturing. It functions as a pH regulator and neutralizing agent.

This versatile chemical serves as a curing component in a broad range of formulated products. In architectural and industrial coatings, MIPA neutralizes acidic resins to improve emulsion stability and adjust pH levels.

Personal care formulators use it to neutralize carbomer and acrylate polymers in gels, creams, and lotions. Controlled viscosity and pH are critical to finished product performance in these specific applications.

In adhesive and sealant systems, it acts as a crosslinking agent and curing accelerator for epoxy and polyurethane formulations. This ensures structural integrity and performance in industrial bonding.

Pharmaceutical manufacturers source MIPA as a buffering agent in topical preparations. Consistent pH directly affects stability and regulatory compliance for medical and therapeutic consumer products.

Isopropanolamine is supplied as a clear liquid in drum and IBC quantities, with bulk tanker options available. Standard commercial grades include technical and industrial purity levels for coatings.

Pharmaceutical and personal care buyers typically require material meeting USP or equivalent specifications. Suppliers should confirm grade documentation prior to procurement to ensure quality.

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Physical Properties

Melting Point 1.74 °C
Boiling Point 159.46 °C @ Press: 760 Torr
Density 0.9611 g/cm³ @ Temp: 20 °C
Flash Point 165 °F
Appearance colourless liquid
Color Clear
Odor slt ammonia odor
Form Liquid
Water Solubility freely soluble
Vapor Pressure <1 mm Hg ( 20 °C)
Refractive Index n 20/D 1.4478(lit.)
pH 11.3 (10g/l, H2O, 20℃)
Log P -0.93 at 23℃

Safety & Handling (Learn More)

Danger GHS05 GHS07
Hazard Statements
H302 Harmful if swallowed
H312 Harmful in contact with skin
H314 Causes severe skin burns and eye damage
H318 Causes serious eye damage
H402 Harmful to aquatic life
Precautionary Statements
P260 Do not breathe dust/fume/gas/mist/vapours/spray.
P264 Wash … thoroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P273 Avoid release to the environment.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P316 Get emergency medical help immediately.
P317 Get emergency medical help.
P321 Specific treatment (see … on this label).
P330 Rinse mouth.
P363 Wash contaminated clothing before reuse.
P405 Store locked up.
P501 Dispose of contents/container in accordance with local regulations.
P264+P265 Wash … thoroughly after handling.
P301+P317 Get emergency medical help.
P302+P352 IF ON SKIN: Wash with plenty of water.
P304+P340 IF INHALED: Remove person to fresh air and keep comfortable for breathing.
P362+P364 Take off contaminated clothing and wash it before reuse.
P301+P330+P331 Rinse mouth. Do NOT induce vomiting.
P302+P361+P354 IF ON SKIN: Take off immediately all contaminated clothing. Rinse skin with water/shower.
P305+P354+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.

Trade & Regulatory

HS Code 29221980
UN Number 2735
ADR Class 8
Packing Group II
Storage Class 8A - Combustible corrosive hazardous materials
WGK (Germany) 1

Documentation

Other Names

Threamine|Mono-iso-propanolamine|Mipa|alpha-aminoisopropyl alcohol|2-hydroxypropylamine|1-methyl-2-aminoethanol|1-amino-2-propanol|1-Amino-2-Hydroxypropanamine

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