Amines
REACH
Isopropanolamine
CAS Number
78-96-6
EC Number
201-162-7
FEMA Number
FEMA 3965
Abbreviation
MIPA
What is Isopropanolamine?
Isopropanolamine (CAS 78-96-6), also known as MIPA or Threamine, is an amino alcohol used in coatings, personal care, and pharmaceutical manufacturing.
Where is Isopropanolamine used?
- Coatings: neutralizes acidic resins to improve emulsion stability and adjust pH levels
- Personal care: neutralizes carbomer and acrylate polymers in gels, creams, and lotions
- Adhesives and sealants: crosslinking agent and curing accelerator for epoxy and polyurethane formulations
- Pharmaceutical manufacturers source MIPA as a buffering agent in topical preparations.
Good to know: Pharmaceutical and personal care buyers typically require material meeting USP or equivalent specifications; suppliers should confirm grade documentation prior to procurement.
Commercial specifications
- Clear liquid in drum and IBC quantities, with bulk tanker options
- Standard commercial grades include technical and industrial purity levels for coatings
Other Names (Synonyms)
Threamine|Mono-iso-propanolamine|Mipa|alpha-aminoisopropyl alcohol|2-hydroxypropylamine|1-methyl-2-aminoethanol|1-amino-2-propanol|1-Amino-2-Hydroxypropanamine
What are the physical properties of Isopropanolamine?
Melting Point 1.74 °C
Boiling Point 159.46 °C @ Press: 760 Torr
Density 0.9611 g/cm³ @ Temp: 20 °C
Flash Point 165 °F
Appearance colourless liquid
Color Clear
Odor slt ammonia odor
Form Liquid
Water Solubility freely soluble
Vapor Pressure <1 mm Hg ( 20 °C)
Refractive Index n 20/D 1.4478(lit.)
pH 11.3 (10g/l, H2O, 20℃)
Log P -0.93 at 23℃
How is Isopropanolamine classified and handled safely? Learn More
Danger
GHS05· Corrosive GHS07· Irritant
Hazard Statements
H302 Harmful if swallowed
H312 Harmful in contact with skin
H314 Causes severe skin burns and eye damage
H318 Causes serious eye damage
H402 Harmful to aquatic life
Precautionary Statements
P260 Do not breathe dust/fume/gas/mist/vapours/spray.
P264 Wash … thoroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P273 Avoid release to the environment.
Which trade and regulatory codes apply to Isopropanolamine?
HS Code 29221980
UN Number 2735
ADR Class 8
Packing Group II
Storage Class 8A - Combustible corrosive hazardous materials
WGK (Germany) 1