Isopropanolamine
Description
Isopropanolamine (CAS 78-96-6), also known as MIPA or Threamine, is an amino alcohol used across coatings, personal care, and pharmaceutical manufacturing. It functions as a pH regulator and neutralizing agent.
This versatile chemical serves as a curing component in a broad range of formulated products. In architectural and industrial coatings, MIPA neutralizes acidic resins to improve emulsion stability and adjust pH levels.
Personal care formulators use it to neutralize carbomer and acrylate polymers in gels, creams, and lotions. Controlled viscosity and pH are critical to finished product performance in these specific applications.
In adhesive and sealant systems, it acts as a crosslinking agent and curing accelerator for epoxy and polyurethane formulations. This ensures structural integrity and performance in industrial bonding.
Pharmaceutical manufacturers source MIPA as a buffering agent in topical preparations. Consistent pH directly affects stability and regulatory compliance for medical and therapeutic consumer products.
Isopropanolamine is supplied as a clear liquid in drum and IBC quantities, with bulk tanker options available. Standard commercial grades include technical and industrial purity levels for coatings.
Pharmaceutical and personal care buyers typically require material meeting USP or equivalent specifications. Suppliers should confirm grade documentation prior to procurement to ensure quality.
Physical Properties
| Melting Point | 1.74 °C |
| Boiling Point | 159.46 °C @ Press: 760 Torr |
| Density | 0.9611 g/cm³ @ Temp: 20 °C |
| Flash Point | 165 °F |
| Appearance | colourless liquid |
| Color | Clear |
| Odor | slt ammonia odor |
| Form | Liquid |
| Water Solubility | freely soluble |
| Vapor Pressure | <1 mm Hg ( 20 °C) |
| Refractive Index | n 20/D 1.4478(lit.) |
| pH | 11.3 (10g/l, H2O, 20℃) |
| Log P | -0.93 at 23℃ |
Safety & Handling (Learn More)
Trade & Regulatory
| HS Code | 29221980 |
| UN Number | 2735 |
| ADR Class | 8 |
| Packing Group | II |
| Storage Class | 8A - Combustible corrosive hazardous materials |
| WGK (Germany) | 1 |
Documentation
Other Names
Threamine|Mono-iso-propanolamine|Mipa|alpha-aminoisopropyl alcohol|2-hydroxypropylamine|1-methyl-2-aminoethanol|1-amino-2-propanol|1-Amino-2-Hydroxypropanamine
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