Amines REACH

Triisopropanolamine

CAS Number
122-20-3
EC Number
204-504-8
Abbreviation
TIPA

What is Triisopropanolamine?

Triisopropanolamine (CAS 122-20-3), commonly abbreviated as TIPA, is a tertiary alkanolamine used as a pH regulator, chelating agent, and crosslinker.

Where is Triisopropanolamine used?

  • Coatings and adhesives: crosslinking agent and curing accelerator
  • Alkyd and epoxy systems: improves film hardness and adhesion
  • Personal care: neutralizes carbomer and acrylate polymers, adjusting pH in creams, lotions, and gels
  • Water treatment: chelating capacity sequesters calcium and magnesium ions, preventing scale formation in industrial process water
  • Textile and leather processing: pH buffer and auxiliary agent during dyeing and finishing operations
  • Its dual amine-alcohol functionality neutralizes acidic systems and coordinates metal ions.

Commercial specifications

  • Purity levels typically at 85% and 99%
  • Bulk supply in drums and IBC containers

Other Names (Synonyms)

C9H21NO3|TIPA|TRIS(2-HYDROXYPROPYL)AMINE|Tri-2-propanolamine|Tris(2-propanol)amine|Tris(2-hydroxy-1-propyl)amine|2-Propanol, 1,1',1''-nitrilotri-|2-Propanol, 1,1',1''-nitrilotris-

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What are the physical properties of Triisopropanolamine?

Melting Point 45 °C
Boiling Point 306 °C
Density 1.0 g/cm³
Flash Point 160 °C
Appearance white to slightly yellow crystalline low
Color White to slightly yellow
Form Crystalline Low Melting Solid
Water Solubility Soluble
Vapor Pressure 1 hPa (100 °C)
Refractive Index 1.4200 (estimate)
pH 10.8 (100g/l, H2O, 20℃)
Log P -0.015 at 23℃

How is Triisopropanolamine classified and handled safely? Learn More

Warning
GHS07· Irritant GHS05· Corrosive

Hazard Statements

H315 Causes skin irritation
H318 Causes serious eye damage
H319 Causes serious eye irritation
H335 May cause respiratory irritation
H336 May cause drowsiness or dizziness
H412 Harmful to aquatic life with long lasting effects

Precautionary Statements

P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash … thoroughly after handling.
P271 Use only outdoors or in a well-ventilated area.
P273 Avoid release to the environment.

Which trade and regulatory codes apply to Triisopropanolamine?

HS Code 29221990
UN Number 3259
ADR Class 8
Packing Group II
Storage Class 11 - Combustible Solids
WGK (Germany) 1
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