Amines REACH

Propylamine

CAS Number
107-10-8
EC Number
203-462-3
Chemical Formula
C3H9N
Molecular Weight
59.11 g/mol
FEMA Number
FEMA 4237

Description

Propylamine (CAS 107-10-8) is a primary aliphatic amine used as a reactive intermediate and pH modifier across pharmaceutical, polymer, and flavor chemistry. With FEMA 4237 status, it is also recognized in flavor applications under regulated conditions. Its reactivity toward carbonyl compounds, acids, and isocyanates makes it a building block for a broad range of synthesized end products. In pharmaceutical manufacturing, it serves as an intermediate in the synthesis of active ingredients.

It is particularly useful for antihistamines and cardiovascular compounds. Polymer producers use it as a curing agent and cross-linker for epoxy systems, where amine reactivity directly influences cure rate and final mechanical properties. In flavor formulation, it contributes to specific aroma profiles at controlled concentrations under FEMA guidelines. Personal care chemists incorporate it as a pH buffer and neutralizing agent in formulations requiring precise alkalinity control.

Propylamine is supplied as a liquid, typically at high purity grades suited to pharmaceutical and industrial synthesis. Technical grade is standard for polymer and chemical manufacturing applications across various industries. Pharmaceutical-grade material is available where API synthesis or regulated flavor use requires tighter specification and documentation. This ensures compliance with rigorous safety and quality standards for sensitive chemical processes.

Other Names (Synonyms)

Propylamine [UN1277] [Flammable liquid]|Propyl amines|Propanamine, 9CI|N-Propyl amine|N-C3H7NH2|3-AMINOPROPYL|1-Propylamine|1-Propanamine, 3-(C6-12-alkyloxy) derivs.

Key Technical Features

  • High Purity Grade standard
  • Consistent Batch Quality
  • Full Regulatory & REACH Support
  • Global Logistics Network enabled

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Physical Properties

Melting Point -83 °C
Boiling Point 48-49 °C
Density 0.719 g/cm³ @ Temp: 20 °C
Flash Point −35 °F
Appearance n-Propylamine is a water-white liquid with a strong irritating odor similar to that of ammonia
Color Clear colorless to pale yellow
Odor ammoniacal
Form Liquid
Water Solubility soluble
Vapor Pressure 4.79 psi ( 20 °C)
Refractive Index n 20/D 1.388(lit.)
pH 12.6 (100g/l, H2O, 20℃)
Log P 0.55

Documentation

Safety & Handling Learn More

Danger
GHS02· Flammable GHS05· Corrosive GHS06· Toxic GHS07· Irritant

Hazard Statements

H225 Highly Flammable liquid and vapor
H290 May be corrosive to metals
H302 Harmful if swallowed
H311 Toxic in contact with skin

Precautionary Statements

P210 Keep away from heat, hot surfaces, sparks, open flames and other ignition sources. No smoking.
P233 Keep container tightly closed.
P234 Keep only in original packaging.
P240 Ground and bond container and receiving equipment.

Trade & Regulatory

HS Code 29211990
UN Number 1277
ADR Class 3
Packing Group II
Storage Class 3 - Flammable liquids
WGK (Germany) 1
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