SoleChem

Propylamine

Amines Personal Care & Cosmetics
CAS
107-10-8
EC
203-462-3
Mol. Weight
59.11 g/mol

Description

Propylamine (CAS 107-10-8) is a primary aliphatic amine used as a reactive intermediate and pH modifier across pharmaceutical, polymer, and flavor chemistry. With FEMA 4237 status, it is also recognized in flavor applications under regulated conditions.

Its reactivity toward carbonyl compounds, acids, and isocyanates makes it a building block for a broad range of synthesized end products. In pharmaceutical manufacturing, it serves as an intermediate in the synthesis of active ingredients.

It is particularly useful for antihistamines and cardiovascular compounds. Polymer producers use it as a curing agent and cross-linker for epoxy systems, where amine reactivity directly influences cure rate and final mechanical properties.

In flavor formulation, it contributes to specific aroma profiles at controlled concentrations under FEMA guidelines. Personal care chemists incorporate it as a pH buffer and neutralizing agent in formulations requiring precise alkalinity control.

Propylamine is supplied as a liquid, typically at high purity grades suited to pharmaceutical and industrial synthesis. Technical grade is standard for polymer and chemical manufacturing applications across various industries.

Pharmaceutical-grade material is available where API synthesis or regulated flavor use requires tighter specification and documentation. This ensures compliance with rigorous safety and quality standards for sensitive chemical processes.

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Physical Properties

Melting Point -83 °C
Boiling Point 48-49 °C
Density 0.719 g/cm³ @ Temp: 20 °C
Flash Point −35 °F
Appearance n-Propylamine is a water-white liquid with a strong irritating odor similar to that of ammonia
Color Clear colorless to pale yellow
Odor ammoniacal
Form Liquid
Water Solubility soluble
Vapor Pressure 4.79 psi ( 20 °C)
Refractive Index n 20/D 1.388(lit.)
pH 12.6 (100g/l, H2O, 20℃)
Log P 0.55

Safety & Handling (Learn More)

Danger GHS02 GHS05 GHS06 GHS07
Hazard Statements
H225 Highly Flammable liquid and vapor
H290 May be corrosive to metals
H302 Harmful if swallowed
H311 Toxic in contact with skin
H314 Causes severe skin burns and eye damage
H318 Causes serious eye damage
H331 Toxic if inhaled
H335 May cause respiratory irritation
H412 Harmful to aquatic life with long lasting effects
H311+H331 Toxic in contact with skin or if inhaled.
Precautionary Statements
P210 Keep away from heat, hot surfaces, sparks, open flames and other ignition sources. No smoking.
P233 Keep container tightly closed.
P234 Keep only in original packaging.
P240 Ground and bond container and receiving equipment.
P241 Use explosion-proof [electrical/ventilating/lighting/…] equipment.
P242 Use non-sparking tools.
P243 Take action to prevent static discharges.
P260 Do not breathe dust/fume/gas/mist/vapours/spray.
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P262 Do not get in eyes, on skin, or on clothing.
P264 Wash … thoroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P271 Use only outdoors or in a well-ventilated area.
P273 Avoid release to the environment.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P316 Get emergency medical help immediately.
P317 Get emergency medical help.
P319 Get medical advice/attention if you feel unwell.
P321 Specific treatment (see … on this label).
P330 Rinse mouth.
P363 Wash contaminated clothing before reuse.
P390 Absorb spillage to prevent material damage.
P405 Store locked up.
P406 Store in a corrosion-resistant/… container with a resistant inner liner.
P501 Dispose of contents/container in accordance with local regulations.
P264+P265 Wash … thoroughly after handling.
P301+P317 Get emergency medical help.
P302+P352 IF ON SKIN: Wash with plenty of water.
P304+P340 IF INHALED: Remove person to fresh air and keep comfortable for breathing.
P361+P364 Take off immediately all contaminated clothing and wash it before reuse.
P370+P378 Use … for extinction.
P403+P233 Store in a well-ventilated place. Keep container tightly closed.
P403+P235 Store in a well-ventilated place. Keep cool.
P301+P330+P331 Rinse mouth. Do NOT induce vomiting.
P302+P361+P354 IF ON SKIN: Take off immediately all contaminated clothing. Rinse skin with water/shower.
P303+P361+P353 IF ON SKIN (or hair): Take off immediately all contaminated clothing. Rinse skin with water/shower.
P305+P354+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.

Trade & Regulatory

HS Code 29211990
UN Number 1277
ADR Class 3
Packing Group II
Storage Class 3 - Flammable liquids
WGK (Germany) 1

Documentation

Other Names

Propylamine [UN1277] [Flammable liquid]|Propyl amines|Propanamine, 9CI|N-Propyl amine|N-C3H7NH2|3-AMINOPROPYL|1-Propylamine|1-Propanamine, 3-(C6-12-alkyloxy) derivs.

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