Cyclopropylamine

Cyclopropylamine (CAS 765-30-0) is a strained-ring primary amine used as a reactive building block in pharmaceutical synthesis and specialty polymer chemistry. The abbreviation CPA appears in procurement and research contexts as a recognized shorthand. Its combination of amine reactivity and ring strain makes it a valued intermediate for constructing complex molecular architectures at scale. In pharmaceutical manufacturing, it is incorporated into active pharmaceutical ingredient synthesis.

This chemical is particularly useful in the preparation of kinase inhibitors, antidepressants, and other small-molecule drug candidates where the cyclopropyl motif improves metabolic stability. Polymer chemists use it as a curing agent. It acts as a cross-linker in epoxy and specialty resin systems, where controlled amine reactivity influences final network density and mechanical performance. In agrochemical development, it serves as a key intermediate for herbicide synthesis.

Biotech research applications include its use as a building block for probe compounds and enzyme inhibitors in target-based drug discovery programs. It is supplied as a colorless to pale yellow liquid in various packaging. Options range from small research quantities to bulk drums and IBC containers. Technical and high-purity grades are available, with purity specifications typically from 98% up to 99%+ for pharmaceutical intermediate use.

Certificate of Analysis documentation aligned with GMP procurement requirements is standard for pharma-grade supply. This ensures the material meets the rigorous demands of modern chemical manufacturing and laboratory research.