Amines REACH

3-Morpholinopropylamine

CAS Number
123-00-2
EC Number
204-590-2
Abbreviation
AMPD

What is 3-Morpholinopropylamine?

3-Morpholinopropylamine (CAS 123-00-2), abbreviated AMPD, is a bifunctional amine combining a primary amine and a morpholine ring in one molecule.

Where is 3-Morpholinopropylamine used?

  • Epoxy coatings and adhesives: curing agent and crosslinker for adhesion and chemical resistance
  • Pharmaceuticals: building block for active ingredients and intermediates
  • Water treatment: biocidal agent and corrosion inhibitor additive targeting microbial growth in cooling and process water
  • Polyurethane and polymer systems: reactive catalyst or chain extender influencing cure rates and mechanical properties
  • The morpholine moiety is a recognized pharmacophore in drug design.

Commercial specifications

  • Liquid at standard commercial purities, typically 98% and above
  • Packaging: drums to IBC containers depending on volume and logistics

Other Names (Synonyms)

4-(3-aminopropyl)morpholine|3-morpholin-4-ylpropan-1-amine|n-(3-aminopropyl)morpholine|AMPD

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What are the physical properties of 3-Morpholinopropylamine?

Melting Point -15 °C
Boiling Point 101-102 °C @ Press: 12 Torr
Density 0.9991 g/cm³
Flash Point 210 °F
Appearance Clear liquid
Color Colorless to Almost colorless
Form Liquid
Water Solubility Soluble
Vapor Pressure 11.5Pa at 20℃
Refractive Index n 20/D 1.4761(lit.)
pH 12 (H2O, 20℃)
Log P -1.076 at 20℃ and pH10.81-11.03

How is 3-Morpholinopropylamine classified and handled safely? Learn More

Danger
GHS05· Corrosive GHS07· Irritant

Hazard Statements

H302 Harmful if swallowed
H312 Harmful in contact with skin
H314 Causes severe skin burns and eye damage
H318 Causes serious eye damage

Precautionary Statements

P260 Do not breathe dust/fume/gas/mist/vapours/spray.
P264 Wash … thoroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P280 Wear protective gloves/protective clothing/eye protection/face protection.

Which trade and regulatory codes apply to 3-Morpholinopropylamine?

HS Code 29349990
UN Number 2735
ADR Class 8
Packing Group II
Storage Class 8A - Combustible corrosive hazardous materials
WGK (Germany) 2
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