SoleChem

2-cyanopyridine

CAS
100-70-9
EC
202-880-3
Mol. Weight
104.11 g/mol

Description

2-Cyanopyridine (CAS 100-70-9), also known as 2-CP, is a pyridine-based nitrile intermediate used across pharmaceutical synthesis, agrochemical manufacturing, and specialty chemical production.

It serves primarily as a building block for constructing more complex heterocyclic structures and as a ligand precursor in catalytic systems. In pharmaceutical manufacturing, it is a key synthetic intermediate.

This material is used for active ingredients including antifungals, antivirals, and kinase inhibitors, where the nitrile group undergoes controlled transformation into amidines, tetrazoles, or carboxylic acids.

Agrochemical producers use it to synthesize pyridine-based fungicides and herbicides at commercial scale. In coordination chemistry, it functions as a bidentate ligand component for metal-complex catalysts.

These catalysts are used in fine chemical and polymer processes. Flavor and fragrance formulators also reference it as picolinic acid nitrile in trace-level applications targeting specific aroma profiles.

The product is supplied as a colorless to pale yellow liquid or low-melting solid, depending on purity and storage conditions. It is available in technical and high-purity grades for various uses.

Pharmaceutical-grade material typically meets custom specification requirements for residual solvent and metal content. Packaging ranges from kilogram quantities for R&D sourcing to drum and IBC volumes.

Industrial-scale procurement is supported by our global logistics network. We ensure all batches meet rigorous internal quality controls to guarantee consistency and performance in your chemical processes.

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Physical Properties

Melting Point 29 °C
Boiling Point 224.5 °C
Density 1.0810 g/cm³ @ Temp: 25 °C
Flash Point 193 °F
Appearance The cyanopyridines are as follows: 2-cyano-: A white to tan liquid or solid. Almond odor. Boiling point=2213℃ ; freezing/melting point=27℃ ; flash point=89℃ . 3-cyano-: a colorless liquid or gray crystal- line solid.
Color White to brown
Form Low Melting Crystalline Solid
Water Solubility immiscible
Vapor Pressure 11.96Pa at 25℃
Refractive Index n 20/D 1.529(lit.)
pH 8.4 (100g/l, H2O)
Log P 0.45 at 25℃

Safety & Handling (Learn More)

Warning GHS07
Hazard Statements
H302 H302
H315 H315
H319 H319
H335 H335
Precautionary Statements
P261 P261
P264 P264
P270 P270
P271 P271
P280 P280
P319 P319
P321 P321
P330 P330
P405 P405
P501 P501
P264+P265 P264+P265
P301+P317 P301+P317
P302+P352 P302+P352
P304+P340 P304+P340
P332+P317 P332+P317
P337+P317 P337+P317
P362+P364 P362+P364
P403+P233 P403+P233
P305+P351+P338 P305+P351+P338

Trade & Regulatory

HS Code 29333999
Storage Class 6.1C - Combustible acute toxic Cat.3 toxic compounds or compounds which causing chronic effects
WGK (Germany) 3

Documentation

Other Names

2-Pyridinecarbonitrile|pyridine-2-carbonitrile|Picolinic acid nitrile|2-Pyridyl nitrile|2-Pyridinecarboxylic acid, nitrile|RefChem:483357|2-Pyridinenitrile|2-CP.|2-CP

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