2-chloronicotinic acid

CAS Number
2942-59-8
EC Number
220-937-0

What is 2-chloronicotinic acid?

2-Chloronicotinic acid (CAS 2942-59-8) is a halogenated pyridinecarboxylic acid; a building block in pharmaceutical synthesis and agrochemical manufacturing.

Where is 2-chloronicotinic acid used?

  • Pharmaceutical development: key intermediate for antiviral, antibacterial and CNS-targeted active ingredients
  • Agrochemicals: herbicide and fungicide active substances, with the chloropyridine scaffold contributing to biological activity
  • Specialty chemicals: precursor for flame retardant additives and catalyst components in polymer processing
  • Personal care and textiles: surface modification agents and preservation chemistry
  • Its reactive chloro and carboxylic acid groups make it an intermediate for complex heterocyclic structures.

Commercial specifications

  • Purity typically 98% or above, confirmed by HPLC
  • Technical grade and high-purity grades for pharmaceutical intermediate use
  • Packaging from small R&D quantities to bulk industrial-scale synthesis

Other Names (Synonyms)

2-Chloropyridine-3-carboxylic acid|2-Chloro-3-pyridinecarboxylic acid|3-Pyridinecarboxylic acid, 2-chloro-|Nicotinic acid, 2-chloro-|3-Carboxy-2-chloropyridine|CNIS

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What are the physical properties of 2-chloronicotinic acid?

Melting Point 194.00 °C
Boiling Point 316.8±22.0 °C(Predicted)
Density 1.470±0.06 g/cm3(Predicted)
Appearance White to cream powder
Color White to cream
Odor Pungent odor
Form Powder
Log P 0.988

How is 2-chloronicotinic acid classified and handled safely? Learn More

Warning
GHS07· Irritant

Hazard Statements

H315 Causes skin irritation
H319 Causes serious eye irritation
H335 May cause respiratory irritation

Precautionary Statements

P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash … thoroughly after handling.
P271 Use only outdoors or in a well-ventilated area.
P280 Wear protective gloves/protective clothing/eye protection/face protection.

Which trade and regulatory codes apply to 2-chloronicotinic acid?

HS Code 29333999
Storage Class 11 - Combustible Solids
WGK (Germany) 3
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