2-chloronicotinic acid
Description
2-Chloronicotinic acid (CAS 2942-59-8) is a halogenated pyridinecarboxylic acid used primarily as a building block in pharmaceutical synthesis and agrochemical manufacturing.
Its reactive chloro and carboxylic acid groups make it a reliable intermediate for constructing more complex heterocyclic structures across multiple industries and chemical research applications.
In pharmaceutical development, it serves as a key intermediate in the synthesis of active pharmaceutical ingredients, particularly antiviral, antibacterial, and CNS-targeted compounds.
Agrochemical formulators use it to produce herbicide and fungicide active substances, where the chloropyridine scaffold contributes significantly to the final biological activity.
In specialty chemical manufacturing, it functions as a precursor for flame retardant additives and catalyst components used in various types of polymer processing and stabilization.
Personal care and textile applications draw on its reactivity for surface modification agents and preservation chemistry in formulated products requiring specific chemical stability.
This product is supplied as a white to off-white crystalline powder. Standard commercial offerings include technical grade and high-purity grades suitable for pharmaceutical intermediate use.
Purity levels are typically at 98% or above confirmed by HPLC. Packaging ranges from small quantities for R&D procurement to bulk quantities for industrial-scale synthesis.
Physical Properties
| Melting Point | 194.00 °C |
| Boiling Point | 316.8±22.0 °C(Predicted) |
| Density | 1.470±0.06 g/cm3(Predicted) |
| Appearance | White to cream powder |
| Color | White to cream |
| Odor | Pungent odor |
| Form | Powder |
| Log P | 0.988 |
Safety & Handling (Learn More)
Trade & Regulatory
| HS Code | 29333999 |
| Storage Class | 11 - Combustible Solids |
| WGK (Germany) | 3 |
Documentation
Other Names
2-Chloropyridine-3-carboxylic acid|2-Chloro-3-pyridinecarboxylic acid|3-Pyridinecarboxylic acid, 2-chloro-|Nicotinic acid, 2-chloro-|3-Carboxy-2-chloropyridine|CNIS
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