Chloroacetyl chloride

Chloroacetyl chloride (CAS 79-04-9), also known as CAC, is a highly reactive acylating agent; a key building block in the synthesis of active pharmaceutical ingredients and agrochemical compounds.

Where is Chloroacetyl chloride used?

• Pharmaceutical manufacturing: synthesis of APIs including local anesthetics, cardiovascular drugs and CNS compounds
• Agrochemicals: intermediate for herbicides and fungicides, particularly chloroacetamide-class herbicides
• Biotechnology and life sciences: preparation of reactive intermediates and labeling reagents
• Industrial chemicals: production of thioethers and specialty compounds through nucleophilic substitution
• Its reactivity toward amines, alcohols and other nucleophiles introduces the chloroacetyl group in multi-step synthesis.

Good to know: Corrosive and moisture-sensitive; handle and store accordingly.

Commercial specifications

• Purity commonly 98% or higher
• Drums or ISO containers