Sodium chloroacetate

CAS Number
3926-62-3
EC Number
223-498-3
Abbreviation
SMCA

What is Sodium chloroacetate?

Sodium chloroacetate (CAS 3926-62-3), also sold as Monoxone and abbreviated SMCA, is the sodium salt form of chloroacetic acid; a reactive intermediate and biocidal agent.

Where is Sodium chloroacetate used?

  • Pharmaceutical manufacturing: synthesis of carboxymethyl derivatives and API intermediates
  • Agrochemicals: selective herbicide intermediate for chloroacetic acid-based weed control actives
  • Personal care: production of carboxymethyl cellulose (CMC) and betaine-type surfactants for shampoos and skin cleansers
  • It serves as a biocidal agent controlling microbial growth in specific process environments.

Commercial specifications

  • Purity specifications typically ranging from 97% to 99%+
  • Packaging in bags and drums suited to bulk industrial procurement

Other Names (Synonyms)

Chloroacetic acid sodium salt|Monoxone|Acetic acid, chloro-, sodium salt|Sodium monochloroacetate|Dow defoliant|SMCA|Sodium monochloracetate|Chloroctan sodny

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What are the physical properties of Sodium chloroacetate?

Melting Point 150-200 °C (decomp)
Density 1.87[at 20℃]
Flash Point 270°C
Appearance white crystalline powder
Color White
Form Crystalline Powder
Water Solubility 440 g/L (20 ºC)
Vapor Pressure 0.001Pa at 20℃
Refractive Index 1.438
pH 4.5-9.0 (50g/l, H2O, 20℃)
Log P -3.8 at 20℃

How is Sodium chloroacetate classified and handled safely? Learn More

Danger
GHS06· Toxic GHS09· Environmental Hazard GHS07· Irritant GHS08· Health Hazard

Hazard Statements

H301 Toxic if swallowed
H302 Harmful if swallowed
H313 May be harmful in contact with skin
H315 Causes skin irritation

Precautionary Statements

P203 Obtain, consult and follow expert instructions for use.
P260 Do not breathe dust/fume/gas/mist/vapours/spray.
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash … thoroughly after handling.

Which trade and regulatory codes apply to Sodium chloroacetate?

HS Code 29154000
UN Number 2659
ADR Class 6.1
Packing Group III
Storage Class 6.1D - Non-combustible acute toxic Cat.3 toxic hazardous materials or hazardous materials causing chronic effects
WGK (Germany) 2
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