Sodium methanethiolate

CAS Number
5188-07-8
EC Number
225-969-9
Abbreviation
SMM

What is Sodium methanethiolate?

Sodium methanethiolate (CAS 5188-07-8), also known as sodium thiomethylate, is a reactive organosulfur nucleophile used in pharmaceutical synthesis, agrochemical manufacturing and polymer chemistry.

Where is Sodium methanethiolate used?

  • Pharmaceuticals: intermediate in API synthesis where selective sulfur alkylation is required, including certain antibiotics and cardiovascular compounds
  • Agrochemicals: introduces methylthio functionality into herbicide and pesticide molecules during multi-step synthesis
  • Polymers and plastics: catalyst or chain-transfer agent controlling weight and modifying end-group chemistry
  • Oil and gas: scavenger formulations and pH-regulating additive in refinery process streams
  • It functions as a methylthiolation reagent, introducing the methylthio group into target molecules under controlled reaction conditions.

Commercial specifications

  • Liquid solution, typically aqueous or methanolic, commonly 20% to 40% by weight for industrial use
  • Packaging ranges from drums to IBC totes depending on volume requirements

Other Names (Synonyms)

Sodium thiomethylate|LB29JWW8H7|RefChem:887680|Sodium thiomethoxide|Methanethiol sodium salt|Methanethiol, sodium salt (1:1)|Sodium, (methylthio)-|Sodium methylmercaptide|SMM

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What are the physical properties of Sodium methanethiolate?

Density 1.12[at 20℃]
Flash Point 27°C
Appearance Very faint yellowish red clear liquid
Color White to off-white
Form Powder
Water Solubility soluble
Vapor Pressure 29hPa at 25℃
Log P -2.33 at 20℃

How is Sodium methanethiolate classified and handled safely? Learn More

Danger
GHS02· Flammable GHS05· Corrosive GHS06· Toxic

Hazard Statements

H226 H226
H228 H228
H301 H301
H314 H314
H318 H318

Precautionary Statements

P210 P210
P233 P233
P240 P240
P241 P241

Which trade and regulatory codes apply to Sodium methanethiolate?

HS Code 29309090
UN Number 3263
ADR Class 8
Packing Group III
WGK (Germany) 3
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