Methyl 3-[(2,2-dimethylbutanoyl)thio]propanoate

Methyl 3-[(2,2-dimethylbutanoyl)thio]propanoate (CAS 938063-63-9) is a thioester-functionalized building block used in pharmaceutical synthesis and biotechnology research.

Where is Methyl 3-[(2,2-dimethylbutanoyl)thio]propanoate used?

• Pharmaceutical intermediate synthesis: construction of complex molecules requiring controlled acyl-transfer chemistry under mild conditions
• Biochemical research: substrate to evaluate thioesterase activity
• Pathway characterization and acyltransferase enzyme studies
• Prodrug development: cleavable thioester moiety for controlled release
• Its reactive thioester linkage makes it a practical substrate for enzyme-catalyzed reactions.

Commercial specifications

• Larger quantities on inquiry for process chemistry and industrial scale-up
• Purity typically meets research-grade standards; high-purity lots for GMP-adjacent or preclinical programs
• CoA and spectral data documentation standard for pharmaceutical procurement