2-Thiazolidinone
Description
2-Thiazolidinone (CAS 2682-49-7) is a sulfur-nitrogen heterocyclic building block used in pharmaceutical synthesis and specialty chemical manufacturing. Oxothiazolidine is a recognized alternative name encountered in research and procurement contexts.
Its primary commercial role is as a reactive intermediate and polymerization initiator in the production of active pharmaceutical ingredients and advanced materials. In pharmaceutical development, it serves as a key scaffold for synthesizing biologically active compounds.
This includes antimicrobial and enzyme-inhibitor candidates at the API intermediate stage. Medicinal chemistry programs use it to construct thiazolidinone-based drug candidates, where the ring system is incorporated directly into the final molecular structure.
In polymer chemistry, it functions as a polymerization initiator, enabling controlled synthesis of specialty polymers used in biomedical and industrial applications. Biotechnology researchers also employ it as a synthetic precursor in the preparation of reagents.
2-Thiazolidinone is supplied as a white to off-white crystalline powder. It is available in research quantities through to multi-kilogram commercial lots, with purity grades typically ranging from 97% to 99%+ to meet fine chemical requirements.
Material is generally offered under technical and high-purity specifications suited to GMP-aligned procurement workflows. This ensures the product meets the rigorous demands of modern pharmaceutical and industrial manufacturing processes.
Physical Properties
| Melting Point | 50-51 °C |
| Boiling Point | 138.0-138.5 °C @ Press: 2.5 Torr |
| Density | 1.277 |
| Color | Off-White |
| Form | Solid |
Safety & Handling (Learn More)
Trade & Regulatory
| HS Code | 2934999090 |
Documentation
Other Names
Oxothiazolidine|1,3-thiazolidin-2-one
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