1,2-Ethanediamine, N1,N2-bis[[4-(2-thiazolyl)phenyl]methyl]-
Description
1,2-Ethanediamine, N1,N2-bis[[4-(2-thiazolyl)phenyl]methyl]- (CAS 1507370-40-2), also known commercially as Tionsil 1258, is a specialized diamine compound combining thiazole and phenyl moieties within a symmetrical ethylenediamine backbone.
It functions as a pharmaceutical intermediate and research building block in the synthesis of biologically active molecules targeting specific biochemical pathways. In pharmaceutical development, it serves as a key structural intermediate.
It is used for synthesizing candidate compounds in antimicrobial and antiparasitic drug discovery programs. Medicinal chemistry teams use its bis-thiazolylbenzyl architecture to construct libraries of heterocyclic amines for high-throughput screening.
These libraries are tested against disease-relevant targets. Biotechnology researchers incorporate it into probe molecule synthesis where the thiazole units contribute to selective binding profiles in target-engagement studies.
Contract research organizations sourcing building blocks for small-molecule drug programs evaluate it for multi-step synthesis routes. These routes require a defined, bifunctional diamine scaffold for complex chemical reactions.
Tionsil 1258 is supplied as a solid, typically as a powder or crystalline material, in research and development quantities. These range from milligram to multi-gram scale depending on the specific project requirements.
It is available under research-grade specifications, with purity confirmed by HPLC and NMR characterization data. Custom batch production for preclinical supply can be arranged through specialist fine chemical and API intermediate manufacturers.
Physical Properties
| Color | white to beige |
| Form | powder |
Safety & Handling (Learn More)
Trade & Regulatory
| WGK (Germany) | 3 |
Documentation
Other Names
Tionsil 1258|N,n'-bis[[4-(1,3-thiazol-2-yl)phenyl]methyl]ethane-1,2-diamine|N1,N2-bis[[4-(2-thiazolyl)phenyl]methyl]-1,2-ethanediamine
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