1-(2-Dimethylaminoethyl)piperazine

1-(2-Dimethylaminoethyl)piperazine (CAS 3644-18-6), also known commercially as TAP, is a bifunctional tertiary amine building block used in pharmaceutical synthesis and specialty chemical manufacturing.

Where is 1-(2-Dimethylaminoethyl)piperazine used?

• Pharmaceutical manufacturing: key intermediate in synthesis, notably where piperazine-based structural motifs are required in the final molecule
• Drug development: reactive intermediate for constructing complex nitrogen-containing scaffolds
• Biotechnology: preparation of linkers and conjugates for targeted drug delivery systems
• Specialty polymers: polymerization initiator or catalyst where controlled amine reactivity is required
• In research-scale synthesis it supports the development of heterocyclic compound libraries for high-throughput screening.

Commercial specifications

• Liquid at standard commercial purities, typically 97% to 99%+
• Research quantities through to bulk industrial volumes
• Technical and high-purity grades are the most common specifications in pharmaceutical and biotechnology procurement