Amines
REACH
1,4-dimethylpiperazine
CAS Number
106-58-1
EC Number
203-412-0
Abbreviation
DMP
What is 1,4-dimethylpiperazine?
1,4-Dimethylpiperazine (CAS 106-58-1), commercially known as Texacat DMP, is a tertiary diamine used as a catalyst and curing agent in polymer and specialty chemical manufacturing. Also abbreviated DMP.
Where is 1,4-dimethylpiperazine used?
- Polyurethane: tertiary amine catalyst promoting gel and blow reactions
- Coatings and adhesives: accelerates epoxy curing, controlling open time and film hardness
- Elastomers and sealants: supports cross-linking reactions
- Pharmaceuticals: synthetic intermediate for piperazine-based APIs
- It accelerates reaction systems and acts as a building block in the synthesis of industrial intermediates.
Good to know: Its dimethyl substitution pattern is a specific structural requirement for many complex molecules. Pharmaceutical-grade material meeting tighter impurity profiles is available for API manufacturing, with documentation aligned to ICH guidelines.
Commercial specifications
- Technical grade: purity typically 99% or higher
- Pharmaceutical grade: tighter impurity profiles, documentation aligned to ICH guidelines
- Liquid form, typically in drums or bulk containers
Other Names (Synonyms)
N,N'-dimethylpiperazine|PIPERAZINE, 1,4-DIMETHYL-|Texacat DMP|TF146U602L|DMP
What are the physical properties of 1,4-dimethylpiperazine?
Melting Point -1 °C
Boiling Point 133 °C
Density 0.844 g/mL at 25 °C(lit.)
Flash Point 65 °F
Appearance clear colorless to yellow liquid
Color Clear colorless to yellow
Form Liquid
Water Solubility miscible
Vapor Pressure 20 hPa (20 °C)
Refractive Index n 20/D 1.4463(lit.)
pH 11.4 (H2O)
Log P -0.26 at 20℃
How is 1,4-dimethylpiperazine classified and handled safely? Learn More
Danger
GHS02· Flammable GHS05· Corrosive GHS07· Irritant
Hazard Statements
H225 Highly Flammable liquid and vapor
H226 Flammable liquid and vapor
H302 Harmful if swallowed
H314 Causes severe skin burns and eye damage
H318 Causes serious eye damage
Precautionary Statements
P210 Keep away from heat, hot surfaces, sparks, open flames and other ignition sources. No smoking.
P233 Keep container tightly closed.
P240 Ground and bond container and receiving equipment.
P241 Use explosion-proof [electrical/ventilating/lighting/…] equipment.
Which trade and regulatory codes apply to 1,4-dimethylpiperazine?
HS Code 29335995
UN Number 2924
ADR Class 3
Packing Group II
Storage Class 3 - Flammable liquids
WGK (Germany) 1