2,2-dimethoxypropane

2,2-Dimethoxypropane (CAS 77-76-9), also known as DMP or acetone dimethyl acetal, is a reactive solvent and dehydrating agent.

Where is 2,2-dimethoxypropane used?

• Pharmaceutical synthesis: protecting carbonyl and hydroxyl groups during multi-step API manufacturing
• Biotech and life sciences: rapid chemical dehydrant for biological sample preparation, particularly electron microscopy tissue processing
• Flavoring intermediate: contributes to production of certain aroma compounds
• Water scavenger and protecting group reagent enabling moisture-sensitive reactions and controlled anhydrous conditions
• It also acts as a solvent where conventional polar aprotic solvents are unsuitable due to moisture sensitivity.

Good to know: Buyers should confirm purity thresholds and water content specifications with suppliers as a critical quality parameter.

Commercial specifications

• Clear liquid in standard drum and IBC quantities
• Bulk availability for industrial-scale procurement
• High-purity grades available for pharmaceutical and analytical laboratory requirements