Dimethoxymethane

CAS Number
109-87-5
EC Number
203-714-2

What is Dimethoxymethane?

Dimethoxymethane (CAS 109-87-5), commercially known as Methylal, is a fast-evaporating solvent used in pharmaceutical manufacturing, specialty chemical synthesis, and flavoring.

Where is Dimethoxymethane used?

  • Pharmaceutical manufacturing: reaction solvent and extraction medium where controlled evaporation and low residual contamination are critical to API quality
  • Flavoring: carrier solvent and flavoring agent for rapid volatilization of aromatic compounds
  • Specialty chemical synthesis: formaldehyde equivalent and catalyst precursor for polyoxymethylene dimethyl ethers and acetal-based intermediates
  • Industrial cleaning and aerosol formulations: co-solvent that improves solvency and reduces VOC content

Good to know: Food-grade and pharmaceutical-grade specifications meet FCC and USP compliance requirements; technical-grade material is standard for industrial solvent use.

Commercial specifications

  • Drum and IBC quantities
  • Bulk tanker options for larger volumes

Other Names (Synonyms)

methylene glycol dimethylether|Methylene dimethyl ether|Methylal|Methoxymethyl methyl ether|Formaldehyde dimethylacetal|dimethyl formal|bis(methyloxy)methane|bis(methoxy)methane

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What are the physical properties of Dimethoxymethane?

Melting Point -105 °C
Boiling Point 41.6 °C @ Press: 760 Torr
Density 0.8593 g/cm³ @ Temp: 20 °C
Flash Point -18 °C
Appearance Methylal is a colorless liquid with a pungent odor.
Color Clear colorless
Odor Mild, ethereal; chloroform-like.
Form Liquid
Water Solubility 32.3 g/100 mL (16 ºC)
Vapor Pressure 6.38 psi ( 20 °C)
Refractive Index n 20/D 1.354
pH pH (12.5vol % , 25℃) : 4.5~6.6
Log P 0

How is Dimethoxymethane classified and handled safely? Learn More

Danger
GHS02· Flammable GHS07· Irritant

Hazard Statements

H225 Highly Flammable liquid and vapor
H315 Causes skin irritation
H319 Causes serious eye irritation
H335 May cause respiratory irritation
H336 May cause drowsiness or dizziness

Precautionary Statements

P210 Keep away from heat, hot surfaces, sparks, open flames and other ignition sources. No smoking.
P233 Keep container tightly closed.
P240 Ground and bond container and receiving equipment.
P241 Use explosion-proof [electrical/ventilating/lighting/…] equipment.

Which trade and regulatory codes apply to Dimethoxymethane?

HS Code 29110000
UN Number 1234
ADR Class 3
Packing Group II
Storage Class 3 - Flammable liquids
WGK (Germany) 1
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