Methyl formate

Methyl formate (CAS 107-31-3), also known as R-611, is a fast-evaporating ester solvent.

Where is Methyl formate used?

• Pharmaceutical manufacturing: reaction solvent and intermediate in synthesis of formic acid, formamide derivatives and active pharmaceutical ingredients
• Fumigation and grain preservation: broad-spectrum biocidal activity against insects and molds in stored commodities
• Flavoring: fruity top-note ingredient in food and beverage formulations
• Industrial foam production: blowing agent alternative under the R-611 designation, replacing more regulated halocarbons in polyurethane systems
• Its high solvency power and reactivity as a formylating agent make it a practical choice for process chemistry and specialty formulations.

Good to know: Proper handling and storage are essential due to the high volatility and flammability of this ester solvent in industrial environments. Grade designations vary by regional market, so technical data sheets should be reviewed for compliance.

Commercial specifications

• Clear liquid in drums, IBCs, and bulk tanker quantities
• Technical grade standard for industrial and fumigation use; higher-purity grades for pharmaceutical and food-grade processing
• High-purity options align with FCC, USP, Ph. Eur., BP, EP, or ACS depending on application
• Buyers should confirm purity specifications and packaging options directly with suppliers