Methanediol

CAS Number
463-57-0
EC Number
207-339-5

What is Methanediol?

Methanediol (CAS 463-57-0), also known as methylene glycol and formaldehyde hydrate, is the stable aqueous form of formaldehyde present in formalin solutions.

Where is Methanediol used?

  • Pharmaceutical manufacturing: buffer systems and controlled formaldehyde-releasing agent for inactivating biological materials in vaccine production
  • Biotechnology and life sciences: tissue fixation and cell preservation protocols
  • Industrial and institutional cleaning: hard surface disinfection where its equilibrium drives antimicrobial efficacy
  • Specialty chemical synthesis: pH-sensitive reactive species in condensation reactions
  • It functions as a reactive intermediate and controlled-release formaldehyde source in industrial and laboratory processes.

Good to know: Precise, aqueous formaldehyde delivery is critical to sample integrity in these specialized fields.

Commercial specifications

  • Aqueous solution, typically commercial formalin at standard concentrations
  • Packaging from laboratory-scale containers to bulk industrial quantities

Other Names (Synonyms)

methylene glycol|formaldehyde hydrate|6Z20YM9257|RefChem:156911|Formaldehyde, monohydrate|Hydrated formaldehyde

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