Glycerol formal

CAS Number
4740-78-7
EC Number
225-248-9

What is Glycerol formal?

Glycerol formal (CAS 4740-78-7), also known as 1,3-Dioxan-5-ol, is a cyclic acetal solvent derived from glycerol that combines low volatility with strong solvency across polar and non-polar systems.

Where is Glycerol formal used?

  • Coatings and adhesives: improves resin compatibility
  • Personal care: humectant and carrier in skin and hair products
  • Industrial and household cleaning concentrates: co-solvent that boosts active ingredient solubility
  • Polymer and elastomer compounders incorporate it as a plasticizer to improve flexibility and processability.

Commercial specifications

  • High purity levels suited for industrial and cosmetic-grade applications
  • Specifications vary by supplier based on purity, water content, and residual acetal profile
  • Packaging ranges from drums to IBC containers

Other Names (Synonyms)

1,3-Dioxan-5-ol|5-Hydroxy-1,3-dioxane|m-Dioxan-5-ol|Glycerol formal, alpha,alpha'|F6UP32GBII|5-Hydroxy-m-dioxane|1,3-Formalglycerol

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What are the physical properties of Glycerol formal?

Boiling Point 50 °C @ Press: 55 Torr
Density 1.2200 g/cm³ @ Temp: 20 °C
Flash Point 97°C
Appearance Clear liquid
Color Colorless to Almost colorless
Form clear liquid
Refractive Index n 20/D 1.451(lit.)

How is Glycerol formal classified and handled safely? Learn More

Warning
GHS07· Irritant

Hazard Statements

H319 Causes serious eye irritation

Precautionary Statements

P280 Wear protective gloves/protective clothing/eye protection/face protection.
P264+P265 Wash … thoroughly after handling.
P337+P317 If eye irritation persists: Get medical advice/attention. Get emergency medical help.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.

Which trade and regulatory codes apply to Glycerol formal?

HS Code 29329900
WGK (Germany) 3
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