Solketal

Solketal (CAS 100-79-8), also known as Glycerol dimethylketal, is a cyclic acetal derived from glycerol used as a solvent, carrier, and chemical intermediate across pharmaceutical, cosmetic, and polymer applications. Its low toxicity profile and biodegradable character make it a preferred alternative to conventional solvents in formulations where regulatory compliance and sustainability drive sourcing decisions.

In pharmaceutical manufacturing, this compound functions as a solvent and carrier for active ingredients, improving solubility and stability in oral and topical drug formulations. Cosmetic formulators incorporate it as a skin-conditioning carrier and co-solvent in serums, creams, and emulsions where clean-label positioning is a priority for the brand.

In polymer and resin chemistry, it acts as a reactive intermediate and crosslinking agent, particularly in the synthesis of specialty polyols and high-performance industrial coatings. It also serves as a stabilizer in fuel blending applications, where it improves cold-flow properties and reduces oxidative degradation in modern biodiesel formulations.

The material is supplied as a clear liquid in drum and IBC quantities suited to industrial procurement. Pharmaceutical-grade material is available to meet USP and BP specifications. Technical-grade product serves polymer and fuel applications. Purity levels typically range from 98% to 99%+ depending on the specific grade and the intended industrial end use.