Diethyl oxalate

CAS Number
95-92-1
EC Number
202-464-1

What is Diethyl oxalate?

Diethyl oxalate (CAS 95-92-1), also known as ethyl oxalate, is the diethyl ester of oxalic acid used primarily as a chemical intermediate and solvent in organic synthesis.

Where is Diethyl oxalate used?

  • Organic synthesis: reactive building block for introducing the oxalyl group into target molecules
  • Specialty chemicals: catalyst precursor
  • Pharmaceutical synthesis: condensation reagent for active pharmaceutical ingredients, particularly barbiturates and antimalarials
  • Heterocyclic compounds: intermediate
  • Personal care: fragrance ingredient and fixative
  • Food flavoring: FEMA-recognized agent imparting fruity, wine-like nuances
  • Catalysis: oxalate precursor for metal oxalate catalyst supports
  • It also serves as an intermediate in various industrial chemical processes.

Good to know: Technical grade and high-purity grades are available to meet the differing requirements of industrial synthesis versus pharmaceutical and flavor applications. Buyers sourcing for regulated end uses should confirm grade specifications and purity certificates.

Commercial specifications

  • Standard commercial packaging ranging from drums to IBC containers for bulk distribution

Other Names (Synonyms)

Ethyl oxalate|Oxalic ether|Ethyl oxalate (VAN)|Diethylester kyseliny stavelove|Ethanedioic acid, 1,2-diethyl ester|Oxalic acid, diethyl ester|Ethanedioic acid, diethyl ester

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What are the physical properties of Diethyl oxalate?

Melting Point -38.5 °C
Boiling Point 185.7 °C @ Press: 760 Torr
Density 1.0785 g/cm³ @ Temp: 20 °C
Flash Point 168 °F
Appearance colourless liquid
Color Clear
Form Liquid
Water Solubility MAY DECOMPOSE
Vapor Pressure 1 mm Hg ( 47 °C)
Refractive Index n 20/D 1.410(lit.)
Log P 0.560

How is Diethyl oxalate classified and handled safely? Learn More

Warning
GHS07· Irritant GHS05· Corrosive GHS08· Health Hazard

Hazard Statements

H227 Combustible liquid
H302 Harmful if swallowed
H314 Causes severe skin burns and eye damage
H315 Causes skin irritation
H319 Causes serious eye irritation
H373 May causes damage to organs through prolonged or repeated exposure

Precautionary Statements

P210 Keep away from heat, hot surfaces, sparks, open flames and other ignition sources. No smoking.
P260 Do not breathe dust/fume/gas/mist/vapours/spray.
P264 Wash … thoroughly after handling.
P270 Do not eat, drink or smoke when using this product.

Which trade and regulatory codes apply to Diethyl oxalate?

HS Code 29171900
UN Number 2525
ADR Class 6.1
Packing Group III
Storage Class 6.1C - Combustible acute toxic Cat.3 toxic compounds or compounds which causing chronic effects
WGK (Germany) 1
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