Diethyl malonate

CAS Number
105-53-3
EC Number
203-305-9
Chemical Formula
C7H12O4
Molecular Weight
160.17 g/mol
FEMA Number
FEMA 2375
Abbreviation
DEM

Description

Diethyl malonate (CAS 105-53-3), also known by the abbreviation DEM or as malonic ester, is a diester compound used as a synthetic intermediate and flavoring agent across food, fragrance, and specialty chemical manufacturing. Its reactivity at the active methylene group makes it a foundational building block for producing pharmaceuticals, agrochemicals, and aroma compounds at industrial scale. In flavor and fragrance production, DEM functions as a precursor to fruity aroma compounds.

The material carries FEMA 2375 status for direct use as a flavoring ingredient. Agrochemical manufacturers rely on it as a key intermediate in synthesizing active ingredients including certain herbicides and insecticides. In pharmaceutical synthesis, it serves as a carbon-chain extender in the production of barbiturates, amino acids, and other active pharmaceutical ingredients. Personal care formulators use it as a carrier solvent and reactive intermediate.

Diethyl malonate is supplied as a clear liquid in drum and IBC quantities, with bulk tanker options available for high-volume buyers. Standard commercial grades include technical and food-grade (FCC) specifications. Purity levels of 99% and above are typical for synthesis-grade material supplied to pharmaceutical and agrochemical customers. Our logistics network ensures reliable delivery of high-purity esters for diverse industrial applications.

Other Names (Synonyms)

Diethyl propanedioate|Ethyl malonate|Malonic ester|Propanedioic acid, diethyl ester|1,3-diethyl propanedioate|Carbethoxyacetic ester|Malonic acid, diethyl ester|Propanedioic acid, 1,3-diethyl ester|DEM

Key Technical Features

  • High Purity Grade standard
  • Consistent Batch Quality
  • Full Regulatory & REACH Support
  • Global Logistics Network enabled

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Physical Properties

Melting Point -50 °C
Boiling Point 199 °C
Density 1.017336 g/cm³ @ Temp: 55.00 °C
Flash Point 212 °F
Appearance colourless liquid
Color colourless liquid
Odor Sweet ester odor
Form Liquid
Water Solubility Miscible with ethyl alcohol, ether, chloroform and benzene. Slightly miscible with water.
Vapor Pressure 1 mm Hg ( 40 °C)
Refractive Index n 20/D 1.413(lit.)
Log P 0.96 at 20℃

Documentation

Safety & Handling Learn More

Warning
GHS07· Irritant

Hazard Statements

H227 Combustible liquid
H319 Causes serious eye irritation
H402 Harmful to aquatic life

Precautionary Statements

P210 Keep away from heat, hot surfaces, sparks, open flames and other ignition sources. No smoking.
P273 Avoid release to the environment.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P403 Store in a well-ventilated place.

Trade & Regulatory

HS Code 29171910
Storage Class 10 - Combustible liquids
WGK (Germany) 1
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