Amines REACH

Diethylamine

CAS Number
109-89-7
EC Number
203-716-3
Abbreviation
DEA

What is Diethylamine?

Diethylamine (CAS 109-89-7), commonly abbreviated as DEA, is a secondary aliphatic amine.

Where is Diethylamine used?

  • Pharmaceutical manufacturing: buffering agent and reaction intermediate in synthesis of active pharmaceutical ingredients, including antihistamines and local anesthetics
  • Agrochemical production: key intermediate for herbicide and fungicide synthesis, particularly dithiocarbamate-based compounds
  • Rubber and polymer production: curing accelerator and cross-linking agent
  • Personal care: pH adjustment systems for creams, lotions, and hair care products
  • It functions as a chemical intermediate, pH buffer, and catalyst in the construction of more complex molecules.

Commercial specifications

  • Concentration typically 99%+ for high-purity grades used in regulated applications
  • Standard commercial grades include technical and pharmaceutical-grade material, with the latter conforming to USP or Ph. Eur. specifications where purity requirements are critical

Other Names (Synonyms)

N,N-Diethylamine|N-Ethylethanamine|Et2NH|(C2H5)2NH|DEA|Ethanamine, N-ethyl-|B035PIS86W

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What are the physical properties of Diethylamine?

Melting Point -50 °C
Boiling Point 55.5 °C
Density 0.7074 g/cm³ @ Temp: 20 °C
Flash Point −20 °F
Appearance Colorless liquid
Color Clear colorless
Odor Ammoniacal; sharp, fishy.
Form Liquid
Water Solubility soluble
Vapor Pressure 14.14 psi ( 55 °C)
Refractive Index n 20/D 1.385(lit.)
pH 13 (100g/l, H2O, 20℃)
Log P 0.58 at 20℃

How is Diethylamine classified and handled safely? Learn More

Danger
GHS02· Flammable GHS05· Corrosive GHS07· Irritant GHS06· Toxic GHS08· Health Hazard

Hazard Statements

H225 Highly Flammable liquid and vapor
H301 Toxic if swallowed
H302 Harmful if swallowed
H311 Toxic in contact with skin

Precautionary Statements

P210 Keep away from heat, hot surfaces, sparks, open flames and other ignition sources. No smoking.
P233 Keep container tightly closed.
P240 Ground and bond container and receiving equipment.
P241 Use explosion-proof [electrical/ventilating/lighting/…] equipment.

Which trade and regulatory codes apply to Diethylamine?

HS Code 29211990
UN Number 1154
ADR Class 3
Packing Group II
Storage Class 3 - Flammable liquids
WGK (Germany) 1
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