Amines REACH

Methyldiethanolamine

CAS Number
105-59-9
EC Number
203-312-7
Abbreviation
MDEA

What is Methyldiethanolamine?

Methyldiethanolamine (CAS 105-59-9), commonly known as MDEA, is a tertiary amine alcohol.

Where is Methyldiethanolamine used?

  • Gas processing: selective acid gas absorbent and pH buffer
  • Natural gas and refinery operations: selective H2S removal from gas streams containing CO2, with lower regeneration energy costs than competing amines
  • Personal care: pH adjuster and neutralizing agent in creams, lotions, and hair care products, with mild conditioning properties
  • Water treatment: pH control and corrosion inhibition in industrial cooling and boiler systems
  • Polymer and coatings chemistry: curing co-agent and crosslinker intermediate in polyurethane and epoxy formulations

Good to know: Pharmaceutical-grade material is available for regulated applications requiring compliance with specific industry safety and purity protocols.

Commercial specifications

  • Concentrations of 99% and above

Other Names (Synonyms)

N-Methyldiethanolamine|2-[2-hydroxyethyl(methyl)amino]ethanol|MDEA

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What are the physical properties of Methyldiethanolamine?

Melting Point -21 °C
Boiling Point 247 °C
Density 1.01728 g/cm³ (liquid) @ Temp: 50 °C; Press: 713 Torr
Flash Point 260 °F
Appearance colourless viscous liquid
Color Clear colorless to light yellow
Odor Ammonical
Form Liquid
Water Solubility MISCIBLE
Vapor Pressure 0.01 mm Hg ( 20 °C)
Refractive Index n 20/D 1.469(lit.)
pH 11.5 (100g/l, H2O, 20℃)
Log P -1.16 at 23℃

How is Methyldiethanolamine classified and handled safely? Learn More

Warning
GHS07· Irritant GHS08· Health Hazard

Hazard Statements

H319 Causes serious eye irritation
H320 Causes eye irritation
H361 Suspected of damaging fertility or the unborn child

Precautionary Statements

P203 Obtain, consult and follow expert instructions for use.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P318 IF exposed or concerned, get medical advice.
P405 Store locked up.

Which trade and regulatory codes apply to Methyldiethanolamine?

HS Code 29221940
Storage Class 10 - Combustible liquids
WGK (Germany) 1
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