Ethyl cyanoacetate

CAS Number
105-56-6
EC Number
203-309-0

What is Ethyl cyanoacetate?

Ethyl cyanoacetate (CAS 105-56-6), also known as cyanoacetic acid ethyl ester, is a reactive ester used as a synthetic intermediate and a flavoring agent.

Where is Ethyl cyanoacetate used?

  • Flavor and fragrance: fruity, wine-like notes in finished compositions
  • Personal care: reactive intermediate in synthesis of active ingredients and specialty esters
  • Monomer and building block: key starting material
  • Production of cyanoacrylate adhesives, pharmaceuticals and agrochemical intermediates
  • Fine chemical and API manufacturing: synthesis of heterocyclic compounds including pyridines and pyrimidines
  • It serves as a staple in modern chemical synthesis.

Good to know: Consistent purity directly affects downstream reaction yields and final product quality. Buyers should confirm purity specifications and packaging options with suppliers based on end-use requirements.

Commercial specifications

  • Standard drum and IBC quantities
  • High-purity grades for flavor and pharmaceutical synthesis

Other Names (Synonyms)

Ethyl 2-cyanoacetate|Ethyl cyanacetate|Cyanoacetic acid ethyl ester|Cyanoacetic ester|Ethyl cyanoethanoate|Acetic acid, cyano-, ethyl ester|Cyanacetate ethyle|USAF KF-25

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What are the physical properties of Ethyl cyanoacetate?

Melting Point -22 °C
Boiling Point 206.0 °C @ Press: 760 Torr
Density 1.0560 g/cm³ @ Temp: 25 °C
Flash Point >230 °F
Appearance Ethyl cyanoacetate is a colorless to straw colored liquid with a mild pleasant odor
Color Clear
Form Liquid
Water Solubility 20 g/L (20 ºC)
Vapor Pressure 1 mm Hg ( 67.8 °C)
Refractive Index n 20/D 1.418(lit.)
Log P -0.119-1.05 at 23-25℃ and pH6.1

How is Ethyl cyanoacetate classified and handled safely? Learn More

Warning
GHS07· Irritant

Hazard Statements

H302 Harmful if swallowed
H312 Harmful in contact with skin
H332 Harmful if inhaled

Precautionary Statements

P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash … thoroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P271 Use only outdoors or in a well-ventilated area.

Which trade and regulatory codes apply to Ethyl cyanoacetate?

HS Code 29269090
Storage Class 10 - Combustible liquids
WGK (Germany) 1
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