Ethyl bromoacetate

Ethyl bromoacetate (CAS 105-36-2), also known commercially as Antol, is a reactive alkylating ester used as a key building block in organic synthesis. It functions primarily as an intermediate in the manufacture of active pharmaceutical ingredients. The compound is essential for specialty chemicals, where its reactive bromomethyl group enables carbon-carbon and carbon-heteroatom bond formation. In pharmaceutical manufacturing, it serves as a precursor in the synthesis of amino acids and peptides.

It is also used for a broad range of API scaffolds requiring acetic acid ester functionalization. Cosmetic and personal care formulators use it as a synthetic intermediate in fragrance molecule production for specific olfactory profiles. The chemical contributes to the construction of esters and lactones. It also has documented use as a biocidal and preservative agent in industrial applications, where its reactivity toward biological nucleophiles provides antimicrobial effect.

In flavor and fragrance chemistry, Antol is referenced as a starting material for aroma compounds requiring bromoacetate chemistry. The product is supplied as a clear to pale yellow liquid for various industrial processes. It is available in technical and reagent grades, with purity specifications typically ranging from 97% to 99%+. Packaging options generally include drums and intermediate bulk containers suited to industrial procurement volumes.