Isobutyl cyanoacetate

Isobutyl cyanoacetate (CAS 13361-31-4) is an ester of cyanoacetic acid used as a reactive intermediate and monomer building block across specialty chemical manufacturing. Its combination of an active methylene group and a nitrile function makes it a practical starting material. This chemical is essential for synthesizing more complex molecules in pharmaceutical and agrochemical production. In pharmaceutical intermediate synthesis, it serves as a precursor in the construction of heterocyclic compounds and active pharmaceutical ingredient scaffolds.

Agrochemical manufacturers use it to produce crop protection compounds, particularly where the cyanoacetate moiety is incorporated into herbicide or pesticide structures. It provides a reliable backbone for these specialized agricultural applications. In polymer chemistry, it functions as a monomer or co-monomer in the preparation of cyanoacrylate-type systems and specialty adhesive formulations. It also supports Knoevenagel condensation reactions at scale for industrial use.

These reactions enable the production of fine chemical intermediates for various downstream applications. Isobutyl cyanoacetate is supplied as a clear liquid in standard packaging suitable for bulk and intermediate-volume procurement. Technical grade is the primary commercially available specification, with purity levels typically confirmed by GC analysis. Suppliers commonly offer this product in drum quantities for diverse manufacturing needs.

Larger bulk arrangements are available through contract or toll manufacturing channels to meet high-volume demand. The material is handled according to standard industrial safety protocols for organic esters and nitriles.