Ethyloctynol
Description
Ethyloctynol (CAS 5877-42-9) is a propargylic alcohol used as a solvent and carrier in pharmaceutical manufacturing. It combines an acetylenic group with a secondary hydroxyl, making it a selective functional building block.
This unique structure is ideal for synthesis workflows where standard alcohols lack the required reactivity profile. In pharmaceutical intermediate synthesis, it serves as a starting material or reactive solvent in the construction of complex ingredients.
Its propargylic alcohol structure supports coupling and reduction reactions used in multi-step API synthesis. Formulators also evaluate it as a carrier solvent in specialized drug delivery systems where conventional glycols are incompatible.
Contract manufacturers working on small-molecule drug candidates source it for exploratory synthesis campaigns. This is particularly useful where structural diversity in the alcohol component is critical for the target chemistry.
Ethyloctynol is typically supplied as a liquid in quantities ranging from laboratory-scale to bulk industrial orders. It is available primarily at technical and research grades, with purity specifications confirmed by GC analysis.
Packaging options generally include glass bottles for small quantities and drums for larger procurement volumes. This ensures safe handling and transport for various industrial and laboratory applications across the chemical sector.
Physical Properties
| Melting Point | 1.9°C (estimate) |
| Boiling Point | 130-132 °C @ Press: 59 Torr |
| Density | 0.873 g/cm³ @ Temp: 20 °C |
| Color | Colorless to Light yellow to Light orange |
| Form | clear liquid |
| Refractive Index | 1.448-1.453 |
Trade & Regulatory
| HS Code | 2905299090 |
Documentation
Other Names
4-ethyl-3-hydroxy-1-octyne|4-ethyloct-1-yn-3-ol|4-ethyl-1-octyn-3-ol
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