3-Hexyne-2,5-diol

3-Hexyne-2,5-diol (CAS 3031-66-1), also marketed as Golpanol HD, is an acetylenic diol used as a reactive intermediate and functional building block across specialty chemical manufacturing. Its dual hydroxyl groups flanking a triple bond make it a targeted starting material for synthesis routes requiring precise stereo- or regiochemical control in complex chemical reactions.

In pharmaceutical manufacturing, it serves as an intermediate in the synthesis of active ingredients and chiral compounds where the acetylenic backbone provides a defined structural scaffold. Polymer chemists use it as a monomer or chain-transfer component in the production of specialty polyurethanes and polyesters, where the alkyne functionality enables post-polymerization modification.

In metalworking and lubricant formulations, it functions as a corrosion inhibitor additive and surface-active component in aqueous cutting fluids for industrial machinery. It also acts as a polymerization initiator in controlled synthesis applications requiring hydroxyl-terminated oligomers, providing stability and reactivity in various chemical environments.

3-Hexyne-2,5-diol is typically supplied as a liquid or low-melting solid depending on purity and temperature conditions. Technical and high-purity grades are available for diverse needs. Purity specifications commonly range from 97% to 99%+ for synthesis-grade applications. Packaging options generally include drum and IBC quantities suited to industrial procurement volumes.