Dimethyl disulfide

CAS Number
624-92-0
EC Number
210-871-0
FEMA Number
FEMA 3536
Abbreviation
DMDS

What is Dimethyl disulfide?

Dimethyl disulfide (CAS 624-92-0), commonly known as DMDS, is an organosulfur compound used across refining, agriculture, and flavor industries. Also called methyl disulfide.

Where is Dimethyl disulfide used?

  • Petroleum refining: presulfiding hydroprocessing catalysts before startup, activating them efficiently
  • Agriculture: soil fumigant and nematicide replacing methyl bromide in pre-plant treatments for high-value crops
  • Food and flavor: FEMA 3536-approved flavoring agent contributing savory, onion, and cooked-meat notes for processed foods and seasonings
  • Biotechnology and fermentation: sulfur source in microbial culture media where controlled sulfur supplementation is required
  • It functions as a sulfiding agent for catalysts and a flavoring ingredient.

Good to know: Presulfiding occurs without requiring hazardous hydrogen sulfide gas handling. Purity grades commonly range from 98% to 99%+ depending on end-use requirements.

Commercial specifications

  • Purity grades commonly range from 98% to 99%+ depending on end-use requirements

Other Names (Synonyms)

Sulfa-hitech 0382|Sulfa-hitech|Methyl disulfide|DMDS|Disulfide dimethyl|2,3-dithiabutane|(methyldithio)methane|(methyldisulfanyl)methane

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What are the physical properties of Dimethyl disulfide?

Melting Point -85 °C
Boiling Point 109.8 °C
Density 1.0625 g/cm³ @ Temp: 20 °C
Flash Point 76 °F
Appearance colourless to yellow liquid with a very unpleasant smell
Color Clear yellow
Odor at 0.10 % in propylene glycol. sulfurous vegetable cabbage onion
Form Liquid
Water Solubility <0.1 g/100 mL at 20 ºC
Vapor Pressure 22 mm Hg ( 20 °C)
Refractive Index n 20/D 1.525(lit.)
Log P 1.91 at 20℃

How is Dimethyl disulfide classified and handled safely? Learn More

Danger
GHS02· Flammable GHS06· Toxic GHS08· Health Hazard GHS09· Environmental Hazard GHS07· Irritant

Hazard Statements

H225 Highly Flammable liquid and vapor
H301 Toxic if swallowed
H302 Harmful if swallowed
H312 Harmful in contact with skin

Precautionary Statements

P203 Obtain, consult and follow expert instructions for use.
P210 Keep away from heat, hot surfaces, sparks, open flames and other ignition sources. No smoking.
P233 Keep container tightly closed.
P240 Ground and bond container and receiving equipment.

Which trade and regulatory codes apply to Dimethyl disulfide?

HS Code 29309070
UN Number 2381
ADR Class 3
Packing Group II
Storage Class 3 - Flammable liquids
WGK (Germany) 2
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