SoleChem

Dipropylenetriamine

CAS
56-18-8
EC
200-261-2
Mol. Weight
131.22 g/mol

Description

Dipropylenetriamine (CAS 56-18-8), also known as DPTA, is a triamine compound used as a building block and intermediate in pharmaceutical and specialty chemical synthesis.

Its three reactive amine groups make it a functional starting material for constructing more complex molecular architectures in drug development and bioconjugation workflows.

In pharmaceutical synthesis, this compound serves as an intermediate for producing active pharmaceutical ingredients and drug candidates requiring polyamine scaffolds.

Biotech and life science researchers use it in linker chemistry and conjugation platforms, where controlled amine reactivity is critical to payload attachment or crosslinking efficiency.

It also finds use in the preparation of chelating agents and polyamine derivatives applied in diagnostic and therapeutic research contexts for various medical applications.

Specialty chemical manufacturers utilize it as a precursor for curing agents, epoxy hardeners, and nitrogen-rich polymer additives in adjacent industrial applications.

The material is available as a liquid at standard commercial purities, with high-purity grades supplied for pharmaceutical and research applications for global clients.

Buyers should confirm purity specifications and documentation requirements, including CoA and residual solvent data, with the supplier prior to procurement of the material.

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Physical Properties

Melting Point -14 °C
Boiling Point 120 °C @ Press: 6 Torr
Density 0.958 g/cm³
Flash Point 245 °F
Appearance colourless to yellow liquid
Color Colorless to Almost colorless
Form clear liquid
Water Solubility Completely miscible in water
Refractive Index n 20/D 1.481(lit.)
Log P -0.826 (est)

Safety & Handling (Learn More)

Danger GHS05 GHS06 GHS07 GHS08
Hazard Statements
H227 Combustible liquid
H302 Harmful if swallowed
H311 Toxic in contact with skin
H314 Causes severe skin burns and eye damage
H317 May cause an allergic skin reaction
H318 Causes serious eye damage
H330 Fatal if inhaled
H341 Suspected of causing genetic defects
H373 May causes damage to organs through prolonged or repeated exposure
Precautionary Statements
P203 Obtain, consult and follow expert instructions for use.
P210 Keep away from heat, hot surfaces, sparks, open flames and other ignition sources. No smoking.
P260 Do not breathe dust/fume/gas/mist/vapours/spray.
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P262 Do not get in eyes, on skin, or on clothing.
P264 Wash … thoroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P271 Use only outdoors or in a well-ventilated area.
P272 Contaminated work clothing should not be allowed out of the workplace.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P284 In case of inadequate ventilation wear respiratory protection.
P316 Get emergency medical help immediately.
P317 Get emergency medical help.
P318 IF exposed or concerned, get medical advice.
P319 Get medical advice/attention if you feel unwell.
P320 Specific treatment is urgent (see … on this label).
P321 Specific treatment (see … on this label).
P330 Rinse mouth.
P363 Wash contaminated clothing before reuse.
P403 Store in a well-ventilated place.
P405 Store locked up.
P501 Dispose of contents/container in accordance with local regulations.
P264+P265 Wash … thoroughly after handling.
P301+P317 Get emergency medical help.
P302+P352 IF ON SKIN: Wash with plenty of water.
P304+P340 IF INHALED: Remove person to fresh air and keep comfortable for breathing.
P333+P317 Get emergency medical help.
P361+P364 Take off immediately all contaminated clothing and wash it before reuse.
P362+P364 Take off contaminated clothing and wash it before reuse.
P370+P378 Use … for extinction.
P403+P233 Store in a well-ventilated place. Keep container tightly closed.
P301+P330+P331 Rinse mouth. Do NOT induce vomiting.
P302+P361+P354 IF ON SKIN: Take off immediately all contaminated clothing. Rinse skin with water/shower.
P305+P354+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.

Trade & Regulatory

HS Code 29252900
UN Number 2269
ADR Class 8
Packing Group III
Storage Class 6.1A - Combustible acute toxic Cat. 1 and 2 very toxic hazardous materials
WGK (Germany) 2

Documentation

Other Names

N-3-aminopropyl-1,3-diaminopropane|N-(3-aminopropyl)propane-1,3-diamine|N-(3-aminopropyl)-1,3-propanediamine|Bis(3-aminopropyl)amine|4-azaheptane-1,7-diamine|3,3'-iminobis(propylamine)|3,3-diaminodipropylamine|1,7-diamino-4-azaheptane

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