Amines REACH

Dipropylenetriamine

CAS Number
56-18-8
EC Number
200-261-2

What is Dipropylenetriamine?

Dipropylenetriamine (CAS 56-18-8), also known as DPTA, is a triamine compound used as a building block and intermediate in pharmaceutical and specialty chemical synthesis.

Where is Dipropylenetriamine used?

  • Pharmaceutical synthesis: intermediate for APIs and drug candidates requiring polyamine scaffolds
  • Drug development and bioconjugation: functional starting material for complex molecular architectures
  • Biotech and life science: linker chemistry and conjugation platforms
  • Diagnostic and therapeutic research: preparation of chelating agents and polyamine derivatives
  • Specialty chemicals: precursor for curing agents, epoxy hardeners and nitrogen-rich polymer additives
  • It serves as a liquid at standard commercial purities.

Good to know: Buyers should confirm purity specifications and documentation requirements, including CoA and residual solvent data, with the supplier prior to procurement.

Commercial specifications

  • High-purity grades for pharmaceutical and research applications

Other Names (Synonyms)

N-3-aminopropyl-1,3-diaminopropane|N-(3-aminopropyl)propane-1,3-diamine|N-(3-aminopropyl)-1,3-propanediamine|Bis(3-aminopropyl)amine|4-azaheptane-1,7-diamine|3,3'-iminobis(propylamine)|3,3-diaminodipropylamine|1,7-diamino-4-azaheptane

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What are the physical properties of Dipropylenetriamine?

Melting Point -14 °C
Boiling Point 120 °C @ Press: 6 Torr
Density 0.958 g/cm³
Flash Point 245 °F
Appearance colourless to yellow liquid
Color Colorless to Almost colorless
Form clear liquid
Water Solubility Completely miscible in water
Refractive Index n 20/D 1.481(lit.)
Log P -0.826 (est)

How is Dipropylenetriamine classified and handled safely? Learn More

Danger
GHS05· Corrosive GHS06· Toxic GHS07· Irritant GHS08· Health Hazard

Hazard Statements

H227 Combustible liquid
H302 Harmful if swallowed
H311 Toxic in contact with skin
H314 Causes severe skin burns and eye damage

Precautionary Statements

P203 Obtain, consult and follow expert instructions for use.
P210 Keep away from heat, hot surfaces, sparks, open flames and other ignition sources. No smoking.
P260 Do not breathe dust/fume/gas/mist/vapours/spray.
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.

Which trade and regulatory codes apply to Dipropylenetriamine?

HS Code 29252900
UN Number 2269
ADR Class 8
Packing Group III
Storage Class 6.1A - Combustible acute toxic Cat. 1 and 2 very toxic hazardous materials
WGK (Germany) 2
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