Amines REACH

Dipropylenetriamine

CAS Number
56-18-8
EC Number
200-261-2
Chemical Formula
C6H17N3
Molecular Weight
131.22 g/mol

Description

Dipropylenetriamine (CAS 56-18-8), also known as DPTA, is a triamine compound used as a building block and intermediate in pharmaceutical and specialty chemical synthesis. Its three reactive amine groups make it a functional starting material for constructing more complex molecular architectures in drug development and bioconjugation workflows.

In pharmaceutical synthesis, this compound serves as an intermediate for producing active pharmaceutical ingredients and drug candidates requiring polyamine scaffolds. Biotech and life science researchers use it in linker chemistry and conjugation platforms, where controlled amine reactivity is critical to payload attachment or crosslinking efficiency.

It also finds use in the preparation of chelating agents and polyamine derivatives applied in diagnostic and therapeutic research contexts for various medical applications. Specialty chemical manufacturers utilize it as a precursor for curing agents, epoxy hardeners, and nitrogen-rich polymer additives in adjacent industrial applications.

The material is available as a liquid at standard commercial purities, with high-purity grades supplied for pharmaceutical and research applications for global clients. Buyers should confirm purity specifications and documentation requirements, including CoA and residual solvent data, with the supplier prior to procurement of the material.

Other Names (Synonyms)

N-3-aminopropyl-1,3-diaminopropane|N-(3-aminopropyl)propane-1,3-diamine|N-(3-aminopropyl)-1,3-propanediamine|Bis(3-aminopropyl)amine|4-azaheptane-1,7-diamine|3,3'-iminobis(propylamine)|3,3-diaminodipropylamine|1,7-diamino-4-azaheptane

Key Technical Features

  • High Purity Grade standard
  • Consistent Batch Quality
  • Full Regulatory & REACH Support
  • Global Logistics Network enabled

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Physical Properties

Melting Point -14 °C
Boiling Point 120 °C @ Press: 6 Torr
Density 0.958 g/cm³
Flash Point 245 °F
Appearance colourless to yellow liquid
Color Colorless to Almost colorless
Form clear liquid
Water Solubility Completely miscible in water
Refractive Index n 20/D 1.481(lit.)
Log P -0.826 (est)

Documentation

Safety & Handling Learn More

Danger
GHS05· Corrosive GHS06· Toxic GHS07· Irritant GHS08· Health Hazard

Hazard Statements

H227 Combustible liquid
H302 Harmful if swallowed
H311 Toxic in contact with skin
H314 Causes severe skin burns and eye damage

Precautionary Statements

P203 Obtain, consult and follow expert instructions for use.
P210 Keep away from heat, hot surfaces, sparks, open flames and other ignition sources. No smoking.
P260 Do not breathe dust/fume/gas/mist/vapours/spray.
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.

Trade & Regulatory

HS Code 29252900
UN Number 2269
ADR Class 8
Packing Group III
Storage Class 6.1A - Combustible acute toxic Cat. 1 and 2 very toxic hazardous materials
WGK (Germany) 2
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