SoleChem

Piperazine

CAS
110-85-0
EC
203-808-3
Mol. Weight
86.14 g/mol

Description

Piperazine (CAS 110-85-0), also known commercially as Vermizine, is a cyclic diamine used as a reactive building block and process chemical across pharmaceutical manufacturing and polymer production.

Its bifunctional amine structure makes it a reliable intermediate for synthesizing active pharmaceutical ingredients and specialty materials. In pharmaceutical manufacturing, it serves as a key structural unit.

This chemical is used in the synthesis of numerous drug compounds, including antipsychotics, antihistamines, and antiparasitic agents. Polymer chemists use it as a curing agent and cross-linker in epoxy resin systems.

Controlled amine reactivity determines final mechanical performance in these systems. It also functions as a monomer in the production of polyamide membranes used in water treatment and industrial filtration.

In agrochemical synthesis, piperazine derivatives are incorporated into fungicide and pesticide formulations as core intermediates. This versatility makes it a staple in modern chemical manufacturing processes.

The product is supplied as white crystalline flakes or anhydrous powder, with piperazine hexahydrate available as an alternative hydrated form. Standard commercial grades include pharmaceutical-grade material.

The material meets USP and BP specifications, as well as technical-grade product for industrial polymer and chemical synthesis applications. Bulk quantities are typically offered in multi-kilogram bags.

These drums are suited to industrial procurement volumes and large-scale manufacturing needs. The material is handled according to strict safety protocols to ensure consistent quality and performance in all applications.

Contact us for supply of Piperazine

Request Quote

Physical Properties

Melting Point 106 °C
Boiling Point 146 °C @ Press: 760 Torr
Density 1.1 g/cm³
Flash Point 65 °C
Appearance Solid
Color White to slightly yellow
Odor at 0.10 % in dipropylene glycol. ammoniacal
Form Crystalline Flakes
Water Solubility 150 g/L (20 ºC)
Vapor Pressure 0.8 mm Hg ( 20 °C)
Refractive Index 1.4460
pH 11.0-12.5 (25℃, 0.1M in H2O)
Log P -1.24 at 20-25℃

Safety & Handling (Learn More)

Danger GHS05 GHS08 GHS02 GHS07
Hazard Statements
H228 Flammable solid
H302 Harmful if swallowed
H312 Harmful in contact with skin
H314 Causes severe skin burns and eye damage
H317 May cause an allergic skin reaction
H318 Causes serious eye damage
H332 Harmful if inhaled
H334 May cause allergy or asthma symptoms or breathing difficulties if inhaled
H335 May cause respiratory irritation
H361 Suspected of damaging fertility or the unborn child
H370 Causes damage to organs
H371 May cause damage to organs
H372 Causes damage to organs through prolonged or repeated exposure
H373 May causes damage to organs through prolonged or repeated exposure
H402 Harmful to aquatic life
Precautionary Statements
P203 Obtain, consult and follow expert instructions for use.
P210 Keep away from heat, hot surfaces, sparks, open flames and other ignition sources. No smoking.
P233 Keep container tightly closed.
P240 Ground and bond container and receiving equipment.
P241 Use explosion-proof [electrical/ventilating/lighting/…] equipment.
P260 Do not breathe dust/fume/gas/mist/vapours/spray.
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash … thoroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P271 Use only outdoors or in a well-ventilated area.
P272 Contaminated work clothing should not be allowed out of the workplace.
P273 Avoid release to the environment.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P284 In case of inadequate ventilation wear respiratory protection.
P316 Get emergency medical help immediately.
P317 Get emergency medical help.
P318 IF exposed or concerned, get medical advice.
P319 Get medical advice/attention if you feel unwell.
P321 Specific treatment (see … on this label).
P330 Rinse mouth.
P363 Wash contaminated clothing before reuse.
P403 Store in a well-ventilated place.
P405 Store locked up.
P501 Dispose of contents/container in accordance with local regulations.
P264+P265 Wash … thoroughly after handling.
P301+P317 Get emergency medical help.
P302+P352 IF ON SKIN: Wash with plenty of water.
P304+P340 IF INHALED: Remove person to fresh air and keep comfortable for breathing.
P308+P316 Get emergency medical help immediately.
P333+P317 Get emergency medical help.
P342+P316 Get emergency medical help immediately.
P362+P364 Take off contaminated clothing and wash it before reuse.
P370+P378 Use … for extinction.
P403+P233 Store in a well-ventilated place. Keep container tightly closed.
P301+P330+P331 Rinse mouth. Do NOT induce vomiting.
P302+P361+P354 IF ON SKIN: Take off immediately all contaminated clothing. Rinse skin with water/shower.
P305+P354+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.

Trade & Regulatory

HS Code 29335900
UN Number 2579
ADR Class 8
Packing Group III
Storage Class 4.1B - Flammable solid hazardous materials
WGK (Germany) 1

Documentation

Other Names

Vermizine (tn)|Piperazin|1,4-Diazinane|1,4-Diazacyclohexane|Antiren

Related Products

Need a chemical? Get a quote within 24 hours.

Call Request Quote