4-Phenylpiperidine-4-carboxylic acid
CAS Number
83949-32-0
EC Number
281-391-7
Industries: Pharma & Healthcare
What is 4-Phenylpiperidine-4-carboxylic acid?
A piperidine-based building block (CAS 83949-32-0) used in pharmaceutical synthesis.
Where is 4-Phenylpiperidine-4-carboxylic acid used?
- Medicinal chemistry: building libraries of analgesic, antipsychotic or receptor-modulating candidates
- Lead optimization: molecular design component
- Biotechnology and life sciences research: preparation of reference standards and labeled compounds
- Contract manufacturers and API producers incorporate it at the gram-to-kilogram scale during drug development workflows.
Good to know: It provides a quaternary carbon center with both an amine and a carboxylic acid handle; its rigid piperidine-phenyl scaffold contributes to target selectivity.
Commercial specifications
- Pharmaceutical-grade purity specifications
- Each batch includes certificate of analysis documentation supporting GMP-adjacent procurement requirements
Other Names (Synonyms)
4-Piperidinecarboxylic acid, 4-phenyl-, 4-methylbenzenesulfonate (1:1)|4-methylbenzene-1-sulfonic Acid|4-Phenylpiperidine-4-carboxylic acid, compound with toluene-P-sulphonic acid|4-Phenyl-4-piperidinecarboxylic acid p-toluenesulfonate
What are the physical properties of 4-Phenylpiperidine-4-carboxylic acid?
Melting Point 225-229 °C
Appearance off-white to slightly beige crystalline powder
How is 4-Phenylpiperidine-4-carboxylic acid classified and handled safely? Learn More
Warning
GHS07· Irritant GHS06· Toxic
Which trade and regulatory codes apply to 4-Phenylpiperidine-4-carboxylic acid?
HS Code 29333990