Phenyl (4,6-dimethoxy-2-pyrimidinyl)carbamate

CAS Number
89392-03-0
EC Number
406-600-2
Chemical Formula
C13H13N3O4
Molecular Weight
275.26 g/mol
Industries: Agriculture

Description

Phenyl (4,6-dimethoxy-2-pyrimidinyl)carbamate (CAS 89392-03-0) is a pyrimidine-based carbamate compound used primarily as a chemical intermediate in agrochemical and pharmaceutical synthesis. Its reactive carbamate moiety makes it a key building block for the production of sulfonylurea and related herbicide active ingredients. In agrochemical manufacturing, it serves as a core intermediate.

It is used in the synthesis of sulfonylurea herbicides, which target acetolactate synthase in broadleaf weeds and grasses. This is a widely commercialized mode of action across cereal and rice crop protection products. Pharmaceutical producers use it as a synthetic precursor where controlled introduction of the dimethoxypyrimidine scaffold is required in drug candidate development. It is essential for specific drug sequences.

Contract manufacturers and toll synthesizers source it for multi-step API intermediate sequences requiring a stable, isolable carbamate transfer agent. Its reactivity profile also suits research-scale synthesis programs. It is frequently used for evaluating novel heterocyclic compounds for biological screening. Phenyl (4,6-dimethoxy-2-pyrimidinyl)carbamate is typically supplied as a solid powder or crystalline material.

It is available in technical grade for agrochemical intermediate use, with higher-purity specifications offered for pharmaceutical and research applications. Packaging ranges from laboratory quantities to bulk volumes.

Other Names (Synonyms)

Carbamic acid, N-(4,6-dimethoxy-2-pyrimidinyl)-, phenyl ester|Tego Dispers 651|phenyl N-(4,6-dimethoxypyrimidin-2-yl)carbamate|Phenyl N-(4,6-dimethoxy-2-pyrimidinyl)carbamate

Key Technical Features

  • High Purity Grade standard
  • Consistent Batch Quality
  • Full Regulatory & REACH Support
  • Global Logistics Network enabled

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Physical Properties

Melting Point 119 °C
Boiling Point 250°C[at 101 325 Pa]
Density 1.317±0.06 g/cm3(Predicted)
Appearance Crystalline Powder
Color White to Orange to Green
Form powder to crystal
Water Solubility 61mg/L at 20℃
Vapor Pressure 0.02Pa at 20℃
Log P 2.1 at 25℃

Documentation

Safety & Handling Learn More

Warning
GHS07· Irritant GHS09· Environmental Hazard

Hazard Statements

H302 Harmful if swallowed
H312 Harmful in contact with skin
H315 Causes skin irritation
H317 May cause an allergic skin reaction

Precautionary Statements

P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash … thoroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P271 Use only outdoors or in a well-ventilated area.

Trade & Regulatory

HS Code 2933599590
UN Number 3077
ADR Class 9
Packing Group III
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