2-Phenylimidazoline
Description
2-Phenylimidazoline (CAS 936-49-2) is a cyclic amidine compound used primarily as a catalyst and pharmaceutical intermediate in fine chemical synthesis. It functions as a curing agent accelerator and reaction catalyst in specialized organic chemistry workflows.
In pharmaceutical manufacturing, this compound serves as a key building block for synthesizing active pharmaceutical ingredients and bioactive heterocyclic scaffolds. It acts as a catalyst in epoxy resin curing systems where controlled reactivity is a priority.
Low dosage requirements make it ideal for formulators working with complex resin systems. Biotechnology researchers use it as a synthetic intermediate in the preparation of imidazoline-class compounds studied for receptor binding activity.
It also appears in the production of specialty agrochemicals and fine chemicals where imidazoline ring systems are required structural components. This versatility makes it a staple in modern industrial chemical synthesis and development.
The product is typically supplied as a white to off-white crystalline solid. Standard commercial offerings include technical-grade and high-purity grades with a minimum assay of 98% or higher for sensitive applications.
Pharmaceutical-grade material is available from select manufacturers meeting USP or BP aligned specifications. Packaging ranges from small research quantities to multi-kilogram industrial lots depending on the specific supplier capability.
Quality control ensures that the material meets rigorous standards for moisture content and purity. This ensures consistent performance in both large-scale manufacturing and precision laboratory research environments across the globe.
Physical Properties
| Melting Point | 98-100 °C |
| Boiling Point | 162 °C |
| Density | 1,15 g/cm 3 |
| Flash Point | 201 °C |
| Appearance | LIGHT YELLOW TO YELLOW FLAKES OR CRYST. POWDER |
| Color | Pale brown |
| Odor | Faint odor |
| Form | Powder |
| Water Solubility | SOLUBLE |
| Vapor Pressure | 0.001Pa at 20℃ |
| Refractive Index | 1.5600 (estimate) |
| Log P | 2.45 at 25℃ |
Safety & Handling (Learn More)
Trade & Regulatory
| HS Code | 29332900 |
| UN Number | 3263 |
| ADR Class | 8 |
| Packing Group | II |
| Storage Class | 11 - Combustible Solids |
| WGK (Germany) | 3 |
Documentation
Other Names
2-Phenyl-2-imidazoline|1H-Imidazole, 4,5-dihydro-2-phenyl-|E78R99DCH8|RefChem:478045|2-Imidazoline, 2-phenyl-|4,5-Dihydro-2-phenyl-1H-imidazole
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