SoleChem

2-Phenylimidazoline

CAS
936-49-2
EC
213-313-4
Mol. Weight
146.19 g/mol

Description

2-Phenylimidazoline (CAS 936-49-2) is a cyclic amidine compound used primarily as a catalyst and pharmaceutical intermediate in fine chemical synthesis. It functions as a curing agent accelerator and reaction catalyst in specialized organic chemistry workflows.

In pharmaceutical manufacturing, this compound serves as a key building block for synthesizing active pharmaceutical ingredients and bioactive heterocyclic scaffolds. It acts as a catalyst in epoxy resin curing systems where controlled reactivity is a priority.

Low dosage requirements make it ideal for formulators working with complex resin systems. Biotechnology researchers use it as a synthetic intermediate in the preparation of imidazoline-class compounds studied for receptor binding activity.

It also appears in the production of specialty agrochemicals and fine chemicals where imidazoline ring systems are required structural components. This versatility makes it a staple in modern industrial chemical synthesis and development.

The product is typically supplied as a white to off-white crystalline solid. Standard commercial offerings include technical-grade and high-purity grades with a minimum assay of 98% or higher for sensitive applications.

Pharmaceutical-grade material is available from select manufacturers meeting USP or BP aligned specifications. Packaging ranges from small research quantities to multi-kilogram industrial lots depending on the specific supplier capability.

Quality control ensures that the material meets rigorous standards for moisture content and purity. This ensures consistent performance in both large-scale manufacturing and precision laboratory research environments across the globe.

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Physical Properties

Melting Point 98-100 °C
Boiling Point 162 °C
Density 1,15 g/cm 3
Flash Point 201 °C
Appearance LIGHT YELLOW TO YELLOW FLAKES OR CRYST. POWDER
Color Pale brown
Odor Faint odor
Form Powder
Water Solubility SOLUBLE
Vapor Pressure 0.001Pa at 20℃
Refractive Index 1.5600 (estimate)
Log P 2.45 at 25℃

Safety & Handling (Learn More)

Danger GHS05 GHS07 GHS09
Hazard Statements
H302 Harmful if swallowed
H315 Causes skin irritation
H318 Causes serious eye damage
H319 Causes serious eye irritation
H400 Very toxic to aquatic life
H410 Very toxic to aquatic life with long lasting effects
H411 Toxic to aquatic life with long lasting effects
Precautionary Statements
P264 Wash … thoroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P273 Avoid release to the environment.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P317 Get emergency medical help.
P321 Specific treatment (see … on this label).
P330 Rinse mouth.
P391 Collect spillage.
P501 Dispose of contents/container in accordance with local regulations.
P264+P265 Wash … thoroughly after handling.
P301+P317 Get emergency medical help.
P302+P352 IF ON SKIN: Wash with plenty of water.
P332+P317 Get emergency medical help.
P337+P317 If eye irritation persists: Get medical advice/attention. Get emergency medical help.
P362+P364 Take off contaminated clothing and wash it before reuse.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P305+P354+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.

Trade & Regulatory

HS Code 29332900
UN Number 3263
ADR Class 8
Packing Group II
Storage Class 11 - Combustible Solids
WGK (Germany) 3

Documentation

Other Names

2-Phenyl-2-imidazoline|1H-Imidazole, 4,5-dihydro-2-phenyl-|E78R99DCH8|RefChem:478045|2-Imidazoline, 2-phenyl-|4,5-Dihydro-2-phenyl-1H-imidazole

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