Hydantoin
Description
Hydantoin (CAS 461-72-3), also known as 2,4-imidazolidinedione, is a five-membered heterocyclic compound used primarily as a chemical intermediate and stabilizer across pharmaceutical and personal care manufacturing.
Its core ring structure serves as the synthetic scaffold for a broad range of active ingredients, preservatives, and specialty chemicals. In pharmaceutical synthesis, it is a key precursor for producing amino acids.
The material is utilized via the Bucherer-Bergs reaction, as well as for anticonvulsant drug intermediates such as phenytoin. Personal care formulators use hydantoin-derived compounds as formaldehyde-releasing preservatives.
These derivatives are common in shampoos, conditioners, and skin creams. It also functions as a buffering and stabilizing agent in formulations where controlled pH maintenance extends shelf life or protects sensitive actives.
Industrial chemical producers use it as a building block for specialty agrochemicals and hydantoin-based biocides. These are applied in water treatment and industrial disinfection processes across various sectors.
The product is supplied as a white crystalline powder in technical and pharmaceutical-grade specifications. Pharmaceutical-grade material is available to USP and BP standards for regulated supply chains.
Packaging typically ranges from kilogram-scale laboratory quantities to multi-tonne bulk orders for industrial synthesis applications. This ensures flexibility for both research and large-scale manufacturing needs.
Physical Properties
| Melting Point | 220 °C |
| Boiling Point | 187.47°C (rough estimate) |
| Density | 1.4457 (rough estimate) |
| Appearance | White Solid |
| Color | White to light yellow |
| Form | Fine Powder |
| Water Solubility | SLIGHTLY SOLUBLE |
| Vapor Pressure | 0Pa at 25℃ |
| Refractive Index | 1.5110 (estimate) |
| Log P | -1.69 |
Trade & Regulatory
| HS Code | 29332100 |
| Storage Class | 11 - Combustible Solids |
| WGK (Germany) | 3 |
Documentation
Other Names
imidazole-2,4(3H,5H)-dione|2,4(3H,5H)-imidazoledione|2,4-imidazolidinedione|imidazolidine-2,4-dione|I6208298TA|2-Imidazolin-4(or 5)-one, 2-hydroxy-|2-IMIDAZOLIDINE-DIONE
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