SoleChem

Hydantoin

Heterocyclic Compounds Pharmaceuticals & Healthcare
CAS
461-72-3
EC
207-313-3
Mol. Weight
100.08 g/mol

Description

Hydantoin (CAS 461-72-3), also known as 2,4-imidazolidinedione, is a five-membered heterocyclic compound used primarily as a chemical intermediate and stabilizer across pharmaceutical and personal care manufacturing.

Its core ring structure serves as the synthetic scaffold for a broad range of active ingredients, preservatives, and specialty chemicals. In pharmaceutical synthesis, it is a key precursor for producing amino acids.

The material is utilized via the Bucherer-Bergs reaction, as well as for anticonvulsant drug intermediates such as phenytoin. Personal care formulators use hydantoin-derived compounds as formaldehyde-releasing preservatives.

These derivatives are common in shampoos, conditioners, and skin creams. It also functions as a buffering and stabilizing agent in formulations where controlled pH maintenance extends shelf life or protects sensitive actives.

Industrial chemical producers use it as a building block for specialty agrochemicals and hydantoin-based biocides. These are applied in water treatment and industrial disinfection processes across various sectors.

The product is supplied as a white crystalline powder in technical and pharmaceutical-grade specifications. Pharmaceutical-grade material is available to USP and BP standards for regulated supply chains.

Packaging typically ranges from kilogram-scale laboratory quantities to multi-tonne bulk orders for industrial synthesis applications. This ensures flexibility for both research and large-scale manufacturing needs.

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Physical Properties

Melting Point 220 °C
Boiling Point 187.47°C (rough estimate)
Density 1.4457 (rough estimate)
Appearance White Solid
Color White to light yellow
Form Fine Powder
Water Solubility SLIGHTLY SOLUBLE
Vapor Pressure 0Pa at 25℃
Refractive Index 1.5110 (estimate)
Log P -1.69

Trade & Regulatory

HS Code 29332100
Storage Class 11 - Combustible Solids
WGK (Germany) 3

Documentation

Other Names

imidazole-2,4(3H,5H)-dione|2,4(3H,5H)-imidazoledione|2,4-imidazolidinedione|imidazolidine-2,4-dione|I6208298TA|2-Imidazolin-4(or 5)-one, 2-hydroxy-|2-IMIDAZOLIDINE-DIONE

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