Hydroxyphenoxy propionic acid

Hydroxyphenoxy propionic acid (CAS 94050-90-5), commercially identified by the abbreviation D-HPPA, is a chiral phenoxypropionic acid derivative used as a building block in pharmaceutical synthesis and specialty formulation. Its defined stereochemistry makes it a controlled starting material where enantiomeric purity directly affects downstream product performance. In pharmaceutical manufacturing, D-HPPA serves as a key intermediate in synthesis.

It is particularly useful in the synthesis of optically active active pharmaceutical ingredients where a resolved chiral center is required from the outset. Personal care formulators incorporate it into stabilizer systems. The phenolic functionality contributes to oxidative protection in finished products. Its UV-stabilizing properties are relevant in topical formulations and cosmetic preparations requiring extended shelf stability under light exposure.

The compound also appears in research and development pipelines targeting biocidal or preservative actives derived from hydroxyphenoxy scaffolds. D-HPPA is typically supplied as a white to off-white crystalline powder. It is available in pharmaceutical-grade specifications with documented enantiomeric excess, which is the critical quality parameter for procurement in regulated synthesis workflows. Packaging ranges from laboratory-scale to kilogram lots.