Hydroxyphenoxy propionic acid

CAS Number
94050-90-5
EC Number
407-960-3
Abbreviation
D-HPPA

What is Hydroxyphenoxy propionic acid?

Hydroxyphenoxy propionic acid (CAS 94050-90-5), commercially identified by the abbreviation D-HPPA, is a chiral phenoxypropionic acid derivative used as a building block in pharmaceutical synthesis and specialty formulation.

Where is Hydroxyphenoxy propionic acid used?

  • Pharmaceutical manufacturing: key intermediate in synthesis
  • Synthesis of optically active APIs requiring a resolved chiral center from the outset
  • Personal care: incorporated into stabilizer systems
  • Topical and cosmetic preparations: UV-stabilizing properties for shelf stability under light exposure
  • Research pipelines target biocidal or preservative actives derived from hydroxyphenoxy scaffolds.

Good to know: Its defined stereochemistry makes it a controlled starting material where enantiomeric purity directly affects downstream product performance. Pharmaceutical-grade specifications with documented enantiomeric excess are the critical quality parameter for procurement in regulated synthesis workflows.

Commercial specifications

  • Packaging ranges from laboratory-scale to kilogram lots

Other Names (Synonyms)

(R)-2-(4-Hydroxyphenoxy)propanoic acid|(R)-(+)-2-(4-Hydroxyphenoxy)propionic acid|(2R)-2-(4-hydroxyphenoxy)propanoic acid|Radianskin PW LS|Propanoic acid, 2-(4-hydroxyphenoxy)-, (2R)-|(R)-2-(p-hydroxyphenoxy)propionic acid|WSI8A5QG10|Propanoic acid, 2-(4-hydroxyphenoxy)-, (R)-|D-HPPA

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What are the physical properties of Hydroxyphenoxy propionic acid?

Melting Point 145-148 °C (lit.)
Boiling Point 367.5±17.0 °C(Predicted)
Density 1.302±0.06 g/cm3(Predicted)
Color Off-White
Form Solid
Refractive Index 38 ° (C=0.1, MeOH)

How is Hydroxyphenoxy propionic acid classified and handled safely? Learn More

Danger
GHS05· Corrosive

Hazard Statements

H318 Causes serious eye damage

Precautionary Statements

P280 Wear protective gloves/protective clothing/eye protection/face protection.
P317 Get emergency medical help.
P264+P265 Wash … thoroughly after handling.
P305+P354+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.

Which trade and regulatory codes apply to Hydroxyphenoxy propionic acid?

HS Code 29189900
Storage Class 11 - Combustible Solids
WGK (Germany) 1
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